Clinical trial · Observational
A Comparative Study of GPI's DBS and Pallidotomy in the Treatment of Meige Syndrome
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
In this study, we will compare the degree of postoperative symptom improvement, postoperative complication rate, postoperative quality of life improvement degree of patients with Meige syndrome undergoing pallidotomy (unilateral globus palliotomy) and deep brain stimulation (unilateral globus pallidus) ,in order to get the conclusion of the comparison of the clinical efficacy of the two surgical plans. In addition, possible predictive factors such as age, gender, age of onset, length of disease course, scale baseline score, preoperative brain PET-CT function analysis and other possible predictive factors are added for analysis, in order to find predictive factors that can guide the choice of surgical options.
Conditions
Conditions (9)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Blepharospasm | — | UNRESOLVED | — |
| Blepharospasm of Both Eyelids | — | UNRESOLVED | — |
| Blepharospasm of Left Eyelid | — | UNRESOLVED | — |
| Blepharospasm of Right Eyelid | — | UNRESOLVED | — |
| Blepharospasm Oromandibular Dystonia | — | UNRESOLVED | — |
| Meige Disease | — | UNRESOLVED | — |
| Meige Syndrome | — | UNRESOLVED | — |
| Meigs Syndrome | — | UNRESOLVED | — |
| Meig Syndrome | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| deep brain stimulation | Procedure | — | UNRESOLVED |
| pallidotomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Meige sydrome patients
- interventionNames
- Procedure: pallidotomy
- Procedure: deep brain stimulation
Primary outcomes (2)
- measure
- Symptom
- timeFrame
- 2 years
- description
- spasm of eyelid
- measure
- complications
- timeFrame
- 2 years
- description
- Postoperative complications
Secondary outcomes (2)
- measure
- quality of life
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * Patients confirmed Meige sydrome Exclusion Criteria: * Patients who cannot finish the neurosurgery or the postoperative evaluation
References
Publications (0)
Data not yet available