Clinical trial · Observational
The Effect of Post-voiding Reisdual Urine on Non-muscle Invasive Bladder Cancer Recurrence and Progression
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Although transurethral resection is the main treatment option for stage Ta and T1 disease, relapse is frequently detected. Tumor number, tumor size, T stage, presence of in situ carcinoma and tumor grade are risk factors for recurrence. The relationship between post voiding residual urine volume and bladder tumor recurrence and progression has not been clearly established. The investigators aimed to examine the effect of high post voiding residual urine volume on recurrence and progression based on the hypothesis that tumor cells circulating in the bladder may increase with excess residual urine.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Bladder Cancer Recurrent | — | UNRESOLVED | — |
| Non-Invasive Bladder Urothelial Carcinoma | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (2)
- label
- High residual volume
- description
- Bladder tumor patients with high residual volume
- label
- Low residual volume
- description
- Bladder tumor patients with low residual volume
Primary outcomes (1)
- measure
- Recurrence
- timeFrame
- 1 year
- description
- Non-muscle invasive bladder cancer recurrence rate
Secondary outcomes (1)
- measure
- Progression
- timeFrame
- 1 year
- description
- Non-muscle invasive bladder cancer progression rate
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with transitional cell non-muscle invasive bladder cancer (NMIBC) pathology * Patients with a diagnosis of Bladder cancer (NMIBC) * Patients undergoing transurethral resection for bladder cancer (NMIBC) * ≥18 years old patients Exclusion Criteria: * Non-transitional cell bladder cancers * Patients with muscle-invasive bladder cancer pathology * \<18 years old patients
References
Publications (2)
- RESULTSazuka T, Sakamoto S, Nakamura K, Imamura Y, Yamamoto S, Komiya A, Ichikawa T. Impact of post-void residual urine volume on intravesical recurrence after nephroureterectomy for upper urinary tract urothelial carcinoma. Int J Urol. 2019 Dec;26(12):1106-1112. doi: 10.1111/iju.14103. Epub 2019 Sep 14. PMID 31522458
- RESULTSazuka T, Sakamoto S, Imamura Y, Nakamura K, Yamamoto S, Arai T, Takeuchi N, Komiya A, Teishima J, Ichikawa T. Relationship between post-void residual urine volume, preoperative pyuria and intravesical recurrence after transurethral resection of bladder carcinoma. Int J Urol. 2020 Nov;27(11):1024-1030. doi: 10.1111/iju.14352. Epub 2020 Sep 1. PMID 32875619