Clinical trial · Interventional
Effectiveness of Drainage by PCN vs. JJ in Patients With Symptoms of Obstructive Kidney Disease Caused by Urolithiasis
Effectiveness of Drainage of the Kidney by Percutaneous Nephrostomy Catheter Placement Vs. Retrograde Double J Catheter Placement in Patients With Symptoms of Obstructive Kidney Disease Caused by Urolithiasis
NCT04594161CI-TRIAL-00074508STONEcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To investigate the effectiveness of percutaneous nephrostomy catheter placement versus retrograde double J catheter placement in patients with symptoms of obstructive kidney disease (with either infection and/or pain and/or kidney function deterioration) caused by urolithiasis.
Conditions
Conditions (33)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Calculus Ureteral | — | UNRESOLVED | — |
| Hydronephrosis | — | UNRESOLVED | — |
| Hydronephrosis, Infected | — | UNRESOLVED | — |
| Hydronephrosis; Infection | — | UNRESOLVED | — |
| Hydronephrosis; Obstruction, Renal Calculus | — | UNRESOLVED | — |
| Hydronephrosis; Obstruction, Ureter | — | UNRESOLVED | — |
| Hydronephrosis, Secondary | — | UNRESOLVED | — |
| Kidney Calculi | — | UNRESOLVED | — |
| Kidney Diseases | — | UNRESOLVED | — |
| Kidney Dysfunction | — | UNRESOLVED | — |
| Kidney Failure, Acute | — | UNRESOLVED |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Double J catheter | Device | — | UNRESOLVED |
| Percutaneous Nephrostomy | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Percutaneous Nephrostomy
- description
- drainage of the kidney by means of a percutaneous Nephrostomy
- interventionNames
- Device: Percutaneous Nephrostomy
- type
- ACTIVE_COMPARATOR
- label
- Double J catheter
- description
- drainage of the kidney by means of a double J catheter
- interventionNames
- Device: Double J catheter
Primary outcomes (4)
- measure
- time (hours) to clinical recovery regarding infection
- timeFrame
- 3 months
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: \- In order to be considered eligible to participate in this study, a subject must meet all of the following criteria: * Male/female \>18 year * Symptoms and/or laboratory results indicating obstructive kidney disease with or without infection. * A kidney or ureteral stone is present on ultrasound or CT (max 3 months old prior to presentation) * Both drainage techniques are feasible and safe in opinion of the treating physician (from logistics point of view and in the best interest of the patient). * Willing and able to comply with filling in questionnaires and follow-up regiment Exclusion Criteria: A potential subject who meets any of the following criteria will be excluded from participation in this study: * Analphabetic or not mastering the Dutch language * Pregnancy * Usage of anticoagulation agents other than acetylsalicylic acid. * Contraindication for either technique looking at history and anatomy (e.g. kidney transplant, pouch, Bricker deviation, urethral or ureteral stenosis)
References
Publications (1)
- DERIVEDSchuil HW, Hendriks N, El Alili M, Bosmans JE, Duijnhoven RG, Oskam BCH, Arends TJH, Duijvesz D, Horsch AD, van der Heij B, Tjiam I, van Overhage H, Lamers ABGN, van Delden OM, Scheepens W, Drossaerts JMA, d'Ancona FCH, Boering S, van Uhm JIM, van der Meer RW, van Roijen HJH, de Kiefte M, Hendrix AJM, Weltings S, Pelger RCM, Beerlage HP, Kamphuis GM, Schout BMA. Cost-effectiveness of percutaneous nephrostomy vs JJ stent in obstructive urolithiasis: economic evaluation alongside the STent Or NEphrostomy (STONE) randomised controlled trial. BJU Int. 2026 May;137(5):906-913. doi: 10.1111/bju.70218. Epub 2026 Mar 13. PMID 41830115