Clinical trial · Interventional
Randomized Study of Digital Life Coaching in Myeloma Patients Undergoing Transplantation
Phase II Study of Digital Life Coaching in Multiple Myeloma Patients Undergoing Stem Cell Transplantation
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Autologous stem cell transplantation (SCT) is the standard of care for fit multiple myeloma (MM) patients; however, the first 100 days after SCT are marked by extensive life disruptions. We have found a 56% relative increase in the use of high-risk benzodiazepine and Z-class (B/Z) drugs for anxiety and insomnia among MM patients during this period. Digital life coaching (DLC), whereby trained coaches work longitudinally with patients through phone calls and text messages to accomplish personal goals, may be able to target anxiety and insomnia in a more integrative manner. This study will investigate whether peri-SCT DLC can lower B/Z usage and improve patient-reported well-being.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Multiple Myeloma | Multiple Myeloma | CURATED_EXACT | 0.92 |
| Stem Cell Transplant | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Electronic Handouts | Other | — | UNRESOLVED |
| Pack Health's Digital Life Coaching (DLC) | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Pack Health's Digital Life Coaching (DLC)
- description
- Participants will receive 16 weeks of access to a trained human life coach employed by Pack Health. Coaches will communicate via phone calls, text messages, emails, and links to web-based Pack Health resources plus the addition of generic wellness-related electronic handouts at the time of each email reminder for participant-reported outcome (PRO) assessments
- interventionNames
- Behavioral: Pack Health's Digital Life Coaching (DLC)
- Other: Electronic Handouts
- type
- ACTIVE_COMPARATOR
- label
- Quasi-usual care control arm
- description
- Participants will receive usual supportive care for stem cell transplantation plus the addition of generic wellness-related electronic handouts at the time of each email reminder for participant-reported outcome (PRO) assessments
- interventionNames
- Other: Electronic Handouts
Primary outcomes (5)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Confirmed diagnosis of one of the following (all referred to as multiple myeloma (MM) for the purposes of this protocol): * Multiple myeloma (ICD-10 code: C90.0) * Extramedullary plasmacytoma (ICD-10 code: C90.2) * Planned receipt of autologous stem cell transplantation (SCT) at University of California, San Francisco (UCSF) * Patients undergoing outpatient SCT will be eligible * Patients who received chemomobilization will be eligible * Ability to understand a written informed consent form (ICF) document, and the willingness to sign the ICF document Exclusion Criteria: * Age \< 18 years * SCT as salvage therapy * Patient-assessed lack of sufficient English proficiency * Lack of ownership of a personal smartphone
References
Publications (0)
Data not yet available