Clinical trial · Observational
Identification of Anxiety and Depression in Adolescents/Young Adults (AYA) With Cancer
NCT04589052CI-TRIAL-00073444completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a prospective, multisite (but all within the UTSW IRB), observational study assessing the relationship of hope to anxiety and depression, QoL, and social support over time in the first year after cancer diagnosis or relapse in AYA (ages 15-29 years of age).
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Depression, Anxiety | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Feasibility of a multi-site, multiple time-point psychosocial study for AYA with cancer
- timeFrame
- up to 12 months (+/- one 4 weeks) following enrollment
- description
- * Hypothesis a: Greater than 50% of eligible patients will enroll and complete at least two time points in the study. * Hypothesis b: Enrollment and study completion rates will differ by site, with the site with the most psychosocial risk (low socioeconomic status as measured by insurance type (private, public, uninsured)) having the lowest enrollment and study completion rates. * Hypothesis c: Enrollment and study completion rates will differ by treatment type. Those receiving treatment that has the most frequent clinic/hospital visits (as measured by chemotherapy versus radiation only/surgery only) will have the highest completion rates.
Secondary outcomes (19)
- measure
- Correlation between hope and quality of life (QoL) in AYA cancer patients
- timeFrame
- up to 12 months (+/- one 4 weeks) following enrollment
- description
- \- Hypothesis a: Hope (as measured by Snyder's (1991) Hope Scale, higher scores indicate higher hope) will be positively correlated to QoL (Pediatric Quality of Life Inventory 3.0 - Cancer Module, PedsQL, Varni, 2002; higher scores indicate better quality of life)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 15 Years
- Maximum age
- 29 Years
Show eligibility criteria text
Inclusion Criteria: * Adolescents and young adults (15-17, 18-29 years of age, respectively) with a new or relapse diagnosis of a malignancy * Patients will include those being followed (treatment or observational) for any malignant disorder at Children's Medical Center, UT Southwestern Medical Center, or Parkland Health and Hospital Systems * Patients whose native language is Spanish or English are eligible to participate * Patients may have any life expectancy * Ability to understand and the willingness to sign a written informed consent. Exclusion Criteria: * Patients with clinically apparent cognitive disabilities which would preclude understanding and completion of measures. * Patients with significant medical issues such as delirium which preclude their ability to consent and complete initial measures
References
Publications (0)
Data not yet available
No reference posted for this study.