Clinical trial · Interventional
Lung B.A.S.E.S. 4 Life Mobile Low-dose Computed Tomography (LDCT) Screening: Ages 40-54
Lung B.A.S.E.S 4 Life Mobile Low-dose Computed Tomography (LDCT) Screening: Assessing Incidence and Stage of Lung Cancer Diagnosis in Subjects Ages 40-54 With a 30 Pack Year History or More Within North and South Carolina
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Low-dose CT Screening has been shown in two large trials in the United States (NLST) and Europe (NELSON) to increase overall survival in subjects 55 years of age and older with a strong smoking history. Unfortunately, in both North Carolina (NC) and South Carolina (SC), subjects are found to have the above referenced smoking history prior to reaching the minimum age in these studies. This study is aimed at decreasing the minimum age of screening in a high-risk population.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
| Lung Neoplasms | Lung Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Mobile Low-dose Computed Tomography (LDCT) Screening | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- OTHER
- label
- Single Arm
- description
- Mobile Low-dose Computed Tomography (LDCT) Screening
- interventionNames
- Other: Mobile Low-dose Computed Tomography (LDCT) Screening
Primary outcomes (1)
- measure
- Lung cancer diagnosis rate in individuals 40-54 years of age at their first screening (T0) with mobile low-dose CT.
- timeFrame
- 1 day
- description
- The lung cancer diagnosis variable will be determined for each subject as a binary variable indicating whether or not the subject's T0 screening results in a diagnosis of lung cancer.
Secondary outcomes (4)
- measure
- Lung cancer diagnosis rate in individuals 40-54 years of age at subsequent screening visits (T1 and T2)
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 40 Years
- Maximum age
- 54 Years
Show eligibility criteria text
Inclusion Criteria: * Subject must meet all the following applicable inclusion criteria to participate in this study: 1. Written informed consent and HIPAA authorization for release of personal health information. NOTE: HIPAA authorization may be included in the informed consent or obtained separately. 2. Age 40-54 years at the time of consent. 3. A positive smoking history of greater/equal to 30 pack years and they are either currently smoking or have quit within the last 15 years. 4. Ability to read and understand the English and/or Spanish language. 5. Ability to understand and comply with study procedures for the entire length of the study. Exclusion Criteria: * Subjects meeting any of the criteria below may not participate in the study: 1. Known diagnosis of lung cancer in the past 5 years. 2. Any known contraindication to having a low-dose CT Scan. 3. Known pregnancy.
References
Publications (0)
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