Clinical trial · Observational
INtra-operative Evaluation of a Novel FLUorescENt C-mEt Tracer in Penile and Tongue
NCT04574427CI-TRIAL-00061532INFLUENCEcompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
In this study we evaluate the feasibility of intraoperative visualization of penile and tongue tumours using the fluorescent tracer EMI-137.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Head and Neck Cancer | Malignant Head and Neck Neoplasm | ALIAS | 0.90 |
| Penile Cancer | Malignant Penile Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- tumour visualization by means of c-MET targeted fluores-cence imaging
- timeFrame
- peri-operative
- description
- The feasibility of intraoperative tumour visualization by means of c-MET targeted fluores-cence imaging will be evaluated, and the imaging result will be correlated to the level of c-MET expression determined using standard immunohistochemistry.
Secondary outcomes (2)
- measure
- Lymph node visualization by means of c-MET targeted fluores-cence imaging
- timeFrame
- peri-operative
- description
- Detection and visualization of lymph node metastases in penile and tongue tumour patients
- measure
- Dysplasia or Cis by means of c-MET targeted fluores-cence imaging
- timeFrame
- Peri-operative
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Written informed consent, prior to performing any protocol related procedures. * Age ≥ 18 years at time of study entry. * ≥ T1 penile or tongue squamous cell cancer * Scheduled for surgical primary tumour resection Exclusion Criteria: * Involvement in the planning and/or conduct of the study. * Pregnant woman * Abstaining from usage of two forms of barrier contraceptive or actively planning pregnancy within 90 days. * Severe kidney insufficiency
References
Publications (0)
Data not yet available
No reference posted for this study.