Clinical trial · Observational
Prospective Multicenter Study on Clinical Application of Sonozoid in Thyroid Tumor
Contrast-enhanced Ultrasound in Thyroid Tumor by Sonozoid
NCT04574258CI-TRIAL-00053198completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Sonazoid as a new generation of ultrasound contrast agent. This study based on the features of Sonazoid specific angiography and high mechanical index, the role of Sonazoid in the differential diagnosis of thyroid benign and malignant tumors was explored.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Ultrasound | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Diagnostic performance of contrast-enhanced ultrasound in thyroid tumor by Sonazoid.
- timeFrame
- 10 months
- description
- Pathology as a gold standard, to evaluate the diagnostic performance (sensitivity, specificity and accuracy) in thyroid tumor by Sonazoid.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * (1) The thyroid nodules were mostly solid or solid. * (2) Patients with thyroid nodules to be punctured or surgically removed; * (3) Ability to understand, sign informed consent and agree to participate in the investigator; * (4) No significant risk of bleeding (platelet ≥50x109/L, prothrombin activity ≥50%) Exclusion Criteria: * (1) Patients with a history of neck surgery; * (2) Women during pregnancy and lactation; * (3) Ultrasound contrast agent exposure history within 1 month; * (4) Those who are known to be allergic to ultrasound contrast agents; * (5) Uncontrolled heart failure.
References
Publications (1)
- DERIVEDXiao F, Li JM, Han ZY, Liu FY, Yu J, Xie MX, Zhou P, Liang L, Zhou GM, Che Y, Wang SR, Liu C, Cong ZB, Liang P. Multimodality US versus Thyroid Imaging Reporting and Data System Criteria in Recommending Fine-Needle Aspiration of Thyroid Nodules. Radiology. 2023 Jun;307(5):e221408. doi: 10.1148/radiol.221408. PMID 37367448