Clinical trial · Interventional
Open or Laparoscopic Mesolectal Excision in Low Rectum Cancer
Total Mesorectal Resection With Dissection of the Lateral Pelvic Lymph Nodes in Low Advanced Cancer Rectum Patients; Laparoscopic Versus Open Approach
NCT04561830CI-TRIAL-00047304completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To compare the open approach and the laparoscopic-assisted approach of dissection of lateral lymph nodes in low advanced rectal cancer patients with clinically suspected nodal metastases in terms of safety, technical feasibility, and patient's oncological outcomes.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Rectal Cancer | Malignant Rectal Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| laparoscopic-assited excision of mesorectum with pelvic lymph nodes excision | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- group 1
- description
- underwent laparoscopic-assisted excision of mesorectum
- interventionNames
- Procedure: laparoscopic-assited excision of mesorectum with pelvic lymph nodes excision
- type
- ACTIVE_COMPARATOR
- label
- group 2
- description
- open excision of mesorectum
- interventionNames
- Procedure: laparoscopic-assited excision of mesorectum with pelvic lymph nodes excision
Primary outcomes (3)
- measure
- operative time
- timeFrame
- during operative time
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Patients aged from 20-70 years with * Sure diagnosis of locally advanced (T3 and T4) adenocarcinoma located in the middle or lower part of the rectum * Clinical or radiological evidence of lateral pelvic lymph nodes metastases Exclusion Criteria: * Patients refused to be included in the study, * Patients with concurrent primary cancer in other locations * Patients with recurrent cancer after treatment * Patients with distant metastasis * Previously managed for pelvic cancer
References
Publications (0)
Data not yet available
No reference posted for this study.