Clinical trial · Observational
Intraoperative Examination of Sentinel Node in Endometrial Cancer (TRSGO-SLN-003)
Intraoperative Examination of Sentinel Node for The Decision of Further Lymphadenectomy in Clinical Early Stage Endometrial Cancer: A Diagnostic Study of Turkish Gynecologic Oncology Group (TRSGO-SLN-003)
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
More than half of the cases with macrometastatic sentinel lymph node (SLN) have non-SLN metastasis and leaving these nodes in-situ may impair the survival. This study assessed the diagnostic accuracy of intraoperative SLN frozen section examination and scrape cytology as a possible solution for management of SLN positive patients. Clinical early stage endometrial cancer patients who underwent SLN algorithm and intraoperative frozen section or scrape cytology to evaluate SLN status for metastasis were analyzed retrospectively. Intraoperative examination findings were compared with final pathology results and diagnostic accuracy of frozen section and scrape cytology were evaluated.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Endometrial Cancer | Malignant Endometrial Neoplasm | CURATED_BROADER | 0.80 |
| Sentinel Lymph Node | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Intraoperative examination of sentinel node | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Frozen section
- description
- Patients underwent intraoperative sentinel node examination by frozen section
- interventionNames
- Diagnostic Test: Intraoperative examination of sentinel node
- label
- Scrape cytology
- description
- Patients underwent intraoperative sentinel node examination by scrape cytology
- interventionNames
- Diagnostic Test: Intraoperative examination of sentinel node
Primary outcomes (1)
- measure
- Sensitivity for the diagnosis of metastatic lymph node intraoperatively
- timeFrame
- intraoperative test
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with apparently early stage endometrial cancer whose SLNs were evaluated intraoperatively were included to this study Exclusion Criteria: * Patients with gross metastatic disease * Patients who had contraindications to dyes (iodine allergy or hepatic impairments)
References
Publications (0)
Data not yet available