Clinical trial · Interventional
Does Routine Submucosal Injection Improve Complete Resection of 4-20 mm Neoplastic Colorectal Polyps?
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a prospective, multi-endoscopist, single center, clinical study at tertiary referral center that addresses an important current challenge in the prevention of colorectal cancer (CRC), namely, how to improve the complete removal of CRC precursors. This study will observe the potential benefit of specific polypectomy technique in conjunction with a systematic submucosal injection prior to the polyp resection. This study will evaluate the completeness and incompleteness of the resection of colorectal neoplastic polyps during the procedures.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Cold snare polypectomy in conjunction with a submucosal injection | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Cold snare polypectomy with a submucosal injection
- description
- The procedure will include a cold snare polypectomy with a submucosal injection done prior to the resection.
- interventionNames
- Procedure: Cold snare polypectomy in conjunction with a submucosal injection
Primary outcomes (1)
- measure
- Incomplete resection rate (IRR)
- timeFrame
- Day 1
- description
- The number of incomplete polyps resected after polypectomy, as defined by any neoplastic tissue found in marginal biopsies.
Secondary outcomes (5)
- measure
- Immediate bleeding complications
- timeFrame
- Day 1
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 45 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Signed consent form; aged 45-80 years old, indication to undergo a colonoscopy Exclusion Criteria: * Known inflammatory bowel disease; active colitis; coagulopathy; familial polyposis syndrome; poor general health, defined as an American Society of Anesthesiologists (ASA) physical status class \>3; emergency colonoscopies, hospitalized patients or patients referred from the emergency room.
References
Publications (0)
Data not yet available