Clinical trial · Observational
Clinical and Pathological Characteristics as Prognostic Factors in Locally Advanced Cervical Cancer
Clinical and Pathological Characteristics as Prognostic Factors in Locally Advanced Cervical Cancer: A Retrospective Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Locally advanced cervical cáncer continues to be a public health problem in emergent economies, even though treatment is very well standardized, recurrence rate is still high, making necessary to evaluate prognostic clinical and pathological factors. The aim of this study is to evaluate clinical and pathological prognostic factor in terms of treatment outcomes, disease-free survival (DFS) and overall survival (OS) in a retrospective cohort of patients with LACC treated with standard chemoradiotherapy in a reference center in México.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cervical Cancer | Malignant Cervical Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Descriptive and analytical | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Localy advanced Cervical Cancer
- description
- Patients with Localy advanced Cervical Cancer confirmed by pathology, clinical exams and computed tomography scan, treated with concurrent chemoradiotherapy.
- interventionNames
- Other: Descriptive and analytical
Primary outcomes (1)
- measure
- Analyze the clinical and pathological characteristics as prognostic factor of patients with locally advanced cervical cancer.
- timeFrame
- 5 years
- description
- Analyze the clinical and pathological characteristics of patients with cervical cancer stages IB2 to IVA as prognostic factor in terms of overall survival.
Secondary outcomes (2)
- measure
- Analyze the clinical and pathological characteristics as prognostic factor of patients with locally advanced cervical cancer.
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with cervical cancer clinical stage Ib2-IVa * Treated with concomitant Chemoradiotherapy Exclusion Criteria: * Rare histologies such gastric type adenocarcinoma, neuroendocrine or clear-cell carcinoma * incomplete treatment or not treated with chemoradiotherapy * Two primary malignancies * Insufficient data for analysis.
References
Publications (1)
- DERIVEDGallardo-Alvarado L, Cantu-de Leon D, Ramirez-Morales R, Santiago-Concha G, Barquet-Munoz S, Salcedo-Hernandez R, Reyes C, Perez-Alvarez S, Perez-Montiel D, Perez-Plasencia C, Trejo-Duran E, Galicia JP. Tumor histology is an independent prognostic factor in locally advanced cervical carcinoma: A retrospective study. BMC Cancer. 2022 Apr 13;22(1):401. doi: 10.1186/s12885-022-09506-3. PMID 35418030