Evaluation of The Efficacy and Safety of Tixel Treatment for the Treatment of Facial and/or Scalp Actinic Keratoses

Inclusion Criteria:

* Age 18-80
* Skin Photo type I-VI
* Mild to moderate thickness confluent actinic keratoses located to scalp and/or face
* Subject is willing and able to comply with protocol requirements and all study visits
* Subject has provided a written informed consent

Exclusion Criteria:

* Any patient who has undergone tanning during the 4 weeks prior to any treatment session and/or any patient who plans to undergo tanning during the 4 weeks following any treatment session (patients who may be exposed to the sun for short periods of time occasionally are not contra-indicated as long as they apply a high SPF sunscreen (\>50).
* Current active Herpes Simplex infection.
* Current skin cancer, malignant sites and/or advanced premalignant lesions or moles in the treatment area.
* An impaired immune system condition or use of immunosuppressive medication.
* Collagen disorders, keloid formation and/or abnormal wound healing.
* Any patient who takes or has taken any medications (including via topical application), herbal treatment (oral or topic), food supplements or vitamins, which may cause fragile skin or impaired skin healing during the last 3 months.
* Any patient who has used oral Isotretinoin (Accutane® or Roaccutan®) within 3 months prior to treatment or less.
* Any patient who has a history of bleeding coagulopathies.
* Any patient who has tattoos or permanent makeup in the treated area.
* Any patient who has burned skin, blistered skin, irritated skin, or sensitive skin in any of the areas to be treated.
* Women who are pregnant (as determined by self-reporting), lactating, or less than 3 months post-delivery, possibly pregnant or planning a pregnancy during the study period.
* Currently participating in or recently participated in another clinical trial (within the last 30 days).
* Age below 18 years.
* Subject underwent prior treatments for actinic keratoses including:
* Prior treatment with ablative laser, any laser or photo-dynamic therapy 3 months prior to enrollment.
* Any cryotherapy or electrodessication 6 weeks prior to enrollment.
* Systemic retinoid therapy within 6 months prior to enrollment.
* Topical treatment with 5-Fluorouracil cream and/or imiquimod cream and/or diclofenac gel and/or ingenol mebutate gel 6 months prior to enrollment.
* Face cannot be treated due to dermal disorder other than actinic keratoses, such as infection, surgical treatment etc.
* Subject has a systemic disease manifested by actinic keratoses (e.g. immune suppression).
* Significant systemic illness.