Clinical trial · Interventional
mHealth Mood Management Tool (Actify) to Improve Population-Level Smoking Cessation
An mHealth Mood Management Tool to Improve Population-Level Cessation
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This phase I trial investigates a new smartphone application (called Actify) for improving population-level smoking cessation and mood management. Actify delivers behavioral activation therapy for depression as part of a smoking cessation intervention and will be compared to another smoking cessation smartphone application that is based on current clinical practice guidelines. Participants will be randomly assigned to receive one of two smartphone applications and accompanying text notifications to help with quitting smoking and improved mood.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cigarette Smoking-Related Carcinoma | Cigarette Smoking-Related Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Health Promotion and Education | Other | — | UNRESOLVED |
| Smoking Cessation Intervention (Actify app) | Behavioral | — | UNRESOLVED |
| Smoking Cessation Intervention (Current Standard Care app) | Behavioral | — | UNRESOLVED |
| Survey Administration | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Arm I (Actify, text notifications)
- description
- Participants use Actify app for smoking cessation for 8 weeks. Participants also receive motivational messages and smoking cessation information via text notifications.
- interventionNames
- Other: Health Promotion and Education
- Behavioral: Smoking Cessation Intervention (Actify app)
- Other: Survey Administration
- type
- ACTIVE_COMPARATOR
- label
- Arm II (Current Standard Care, text notifications)
- description
- Participants use app for smoking cessation for 8 weeks. Participants also receive motivational messages and smoking cessation information via text notifications.
- interventionNames
- Other: Health Promotion and Education
- Behavioral: Smoking Cessation Intervention (Current Standard Care app)
- Other: Survey Administration
Primary outcomes (2)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Current smoker, averaging at least 5 cigarettes/day for the last 30 days * Interested in quitting smoking in the next 30 days * Experience downloading and using one or more apps on their smartphone * Either screens negative (Patient Health Questionnaire - 9 Item \[PHQ-9\] score 0-4) for depression or screens positive for mild to moderate current depressive symptoms (PHQ-9 score 5-19) * Willing and able to complete all study activities * Comfortable reading and writing in English * Have a mobile data plan and/or access to WiFi to support the use of the Actify app * Reside in the US * Have a smartphone either an iPhone (running iOS version 11 or higher) or an Android phone (running version 5.0 or higher) Exclusion Criteria: * Currently receiving behavioral treatment for depression (e.g., psychotherapy) * Current use of a depression app * Severe depression (PHQ-9 \>= 20) * Receiving other treatment for smoking cessation * Previous use of the QuitGuide app * Current or recent (within the past year) enrollment in a Fred Hutch smoking cessation study * Employees/family of investigator or study center * Member of the same household as another participant * Woman who is pregnant or breastfeeding, or planning to become pregnant * Currently incarcerated * Is ineligible per fraud prevention protocol
References
Publications (0)
Data not yet available