Clinical trial · Interventional
Mobile Health Application (PACT) to Improve Engagement in Advance Care Planning
Planning Advance Care Together (PACT) to Improve Engagement in Advance Care Planning
NCT04515810CI-TRIAL-00122408recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This clinical trial tests a new mobile health application (app) called Planning Advance Care Together (PACT) to help people with cancer talk about and plan for advance care planning (the care they would want if they were unable to communicate) with their loved ones and doctors. The development of the PACT mobile app may help future patients incorporate their social network (typically, but not exclusively, family) into the advance care planning process.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Locally Advanced Malignant Solid Neoplasm | Malignant Solid Neoplasm | CURATED_BROADER | 0.78 |
| Metastatic Malignant Solid Neoplasm | Malignant Solid Neoplasm | CURATED_BROADER | 0.78 |
| Recurrent Hematologic Malignancy | Hematopoietic and Lymphoid Cell Neoplasm | CURATED_BROADER | 0.78 |
| Refractory Hematologic Malignancy | Hematopoietic and Lymphoid Cell Neoplasm | CURATED_BROADER | 0.78 |
Interventions
Interventions (5)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Best Practice | Other | — | UNRESOLVED |
| Internet-Based Intervention | Other | — | UNRESOLVED |
| Post-intervention qualitative feedback interview | Other | — | UNRESOLVED |
| Questionnaire Administration | Other | — | UNRESOLVED |
| Telephone-Based Intervention | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Arm I (PACT)
- description
- Participants use PACT mHealth app for up to 4 weeks and receive one check-in call on study.
- interventionNames
- Other: Internet-Based Intervention
- Other: Telephone-Based Intervention
- Other: Questionnaire Administration
- Other: Post-intervention qualitative feedback interview
- type
- ACTIVE_COMPARATOR
- label
- Arm II (standard care)
- description
- Participants engage in standard care with no modifications for up to 4 weeks.
- interventionNames
- Other: Best Practice
- Other: Questionnaire Administration
Primary outcomes (24)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * PATIENT: Diagnosis of poor prognosis advanced cancer defined as locally advanced or metastatic solid cancer and/or disease progression following at least first line systemic therapy and/or relapsed or refractory hematologic cancer. * PATIENT: Have internet access through a computer or a mobile device; the principal investigator (PI) will ensure that those who have access to a computer or mobile device have access to a computer or mobile device with internet access to ensure they can complete study procedures. * PATIENT: The ability to provide informed consent. * PATIENT: Identification of a loved support person if one is available; patients who are unable to identify a support person willing to participate with them will be allowed to continue in the study on their own. * PATIENT: 18 years of age or older. * SUPPORT PERSON: The person (family member or friend) whom the patient indicates being a support person. * SUPPORT PERSON: English speaking. * SUPPORT PERSON: 18 years of age or older and able to provide informed consent. * PROVIDER: Current clinical practice and/or research with advanced cancer patients. * PROVIDER: A history of 3+ years working with advanced cancer patients. * PROVIDER: 18 years of age or older. Providers across disciplines (e.g., social work, oncology) will be enrolled. Exclusion Criteria: * PATIENT: Not fluent in English. * PATIENT: Severely cognitively impaired (as measured by Short Portable Mental Status Questionnaire scores of \>= 6) to be delivered by trained study research staff during screening. * PATIENT: Too ill or weak to complete the interviews (as judged by the interviewer). * PATIENT: Currently receiving hospice at the time of enrollment. * PATIENT: Children and young adults under age 18.
References
Publications (32)
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- BACKGROUNDS. Summers and A. Watt,
- BACKGROUNDBorsci S, Federici S, Lauriola M. On the dimensionality of the System Usability Scale: a test of alternative measurement models. Cogn Process. 2009 Aug;10(3):193-7. doi: 10.1007/s10339-009-0268-9. Epub 2009 Jun 30. PMID 19565283
- BACKGROUNDSudore RL, Stewart AL, Knight SJ, McMahan RD, Feuz M, Miao Y, Barnes DE. Development and validation of a questionnaire to detect behavior change in multiple advance care planning behaviors. PLoS One. 2013 Sep 5;8(9):e72465. doi: 10.1371/journal.pone.0072465. eCollection 2013. PMID 24039772
- BACKGROUNDMack JW, Weeks JC, Wright AA, Block SD, Prigerson HG. End-of-life discussions, goal attainment, and distress at the end of life: predictors and outcomes of receipt of care consistent with preferences. J Clin Oncol. 2010 Mar 1;28(7):1203-8. doi: 10.1200/JCO.2009.25.4672. Epub 2010 Feb 1. PMID 20124172
- BACKGROUNDZimet GD, Powell SS, Farley GK, Werkman S, Berkoff KA. Psychometric characteristics of the Multidimensional Scale of Perceived Social Support. J Pers Assess. 1990 Winter;55(3-4):610-7. doi: 10.1080/00223891.1990.9674095. PMID 2280326
- BACKGROUNDKissane DW, McKenzie M, McKenzie DP, Forbes A, O'Neill I, Bloch S. Psychosocial morbidity associated with patterns of family functioning in palliative care: baseline data from the Family Focused Grief Therapy controlled trial. Palliat Med. 2003 Sep;17(6):527-37. doi: 10.1191/0269216303pm808oa.