Clinical trial · Observational
Computer Aided Diagnosis of Colorectal Polyps
Real-Time Artificial Intelligence Aided Diagnosis of Colorectal Polyps During Colonoscopy: A Clinical Trial With the EndoBRAIN Technology
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to assess whether computer aided technology (CAD) can help in the diagnosis of polyps found the bowel compared with visual inspection alone and therefore whether it is beneficial in helping clinicians to decide whether to remove a polyp or not. Presently, most endoscopists remove all polyps found and send them to the laboratory for testing. The number of colonoscopies is increasing, meaning that more polyps are detected and removed. This comes at a significant cost to the health service and increases the time taken to complete a colonoscopy.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colonic Polyp | — | UNRESOLVED | — |
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Endobrain, Computer Aided Diagnosis (CAD) | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Treatment Group
- description
- All patients will undergo CAD of any diminutive polyps found in the rectosigmoid on colonoscopy
- interventionNames
- Diagnostic Test: Endobrain, Computer Aided Diagnosis (CAD)
Primary outcomes (1)
- measure
- True positive adenoma detection rate
- timeFrame
- 6 months
- description
- True positive adenoma detection rate with visual inspection versus true positive adenoma detection rate with visual inspection plus CAD
Secondary outcomes (7)
- measure
- True negative adenoma detection rate
- timeFrame
- 6 months
- description
- True negative adenoma detection rate with visual inspection versus true negative adenoma detection rate with visual inspection plus CAD
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 90 Years
Show eligibility criteria text
Inclusion Criteria: * Individuals 18 years or older who are scheduled for screening, surveillance, diagnostic, or therapeutic colonoscopy at at King's College Hospital with diminutive rectosigmoid polyps. Exclusion Criteria: * Diminutive polyps with known histology * Inflammatory bowel disease * Polyposis syndrome (e.g., familial adenomatous polyposis, serrated polyposis) * History of chemotherapy or radiation therapy for colorectal lesions * Inability to undergo polypectomy (e.g. intake of anticoagulants, comorbidities, or patient refusal) * Pregnancy
References
Publications (0)
Data not yet available