Clinical trial · Observational
Impact of Environmental Exposures on Tumor Risk in Subjects at Risk of Hereditary SDHx Paraganglioma
Impact of Environmental Exposures on Tumor Risk in Subjects at Risk of Hereditary SDHx-related Paragangliomas, Pilot Phase
NCT04481152CI-TRIAL-00117302PGL-EXPO-1completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The main objective of the pilot phase of PGLEXPO will be to assess the faisability and to precise methodology of a case-control study designed for testing the impact of environmental and professional exposures on the tumoral risk in SDHx-mutation carriers
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Environmental Exposure | — | UNRESOLVED | — |
| Genetic Predisposition | — | UNRESOLVED | — |
| SDH Gene Mutation | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Feasability of the protocol of a national case/control study (PGL.EXPO2)
- timeFrame
- 2 years
- description
- Successful pairing of 50 cases with 50 controls
Secondary outcomes (2)
- measure
- Feasibility of matching cases and controls
- timeFrame
- 2 years
- description
- Proportion of cases for which a control could be identified
- measure
- Ease of matching cases and controls
- timeFrame
- 2 years
- description
- Mean number of controls matching for a case
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Cases: SDHx mutation carriers diagnosed for a SDHx-related tumor 2. Controls: SDHx mutation carriers with no SDHx-related tumor Exclusion Criteria: Incapacity to exercise free and informed consent for the study
References
Publications (0)
Data not yet available
No reference posted for this study.