Clinical trial · Interventional
Lay Health Worker Expanded Intervention in Community Oncology Practices
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Undertreated patient symptoms and resulting acute care use require approaches that improve symptom-burden. Previously a lay health worker (LHW)-led symptom screening intervention was developed for patients with cancer. In pilot work, the intervention was associated with improvements in patient symptom burden and reductions in healthcare use and costs of care at the end of life. This intervention will be expanded across several clinics to evaluate the impact of the LHW intervention on with cancer and the LHW will be trained to refer patients to palliative care. This randomized intervention will evaluate the effect on healthcare use, total costs, palliative care and hospice referral.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| End of Life | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Program participants | Behavioral | — | UNRESOLVED |
| Usual Care | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Intervention Group Arm
- description
- Patients randomized into the intervention will be assigned a lay health worker who will contact the patient to begin the intervention. The intervention includes: proactive symptom assessments for patients for up to 12-months.
- interventionNames
- Behavioral: Program participants
- Other: Usual Care
- type
- ACTIVE_COMPARATOR
- label
- Behavioral:Program participants
- description
- The control group arm will receive usual care as provided by their local oncologists.
- interventionNames
- Other: Usual Care
Primary outcomes (2)
- measure
- % of patients with Emergency Department Visit within 12-months after patient enrollment (Chart Review)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 75 Years
- Maximum age
- 100 Years
Show eligibility criteria text
Inclusion Criteria: * Newly diagnosed or relapsed cancer diagnosis. * 75 years or older * Diagnosis of relapse or progressive disease (any cancer diagnosis) as identified by imaging or biopsy and confirmed by physician. * Must have capacity to verbally consent Exclusion Criteria: * Inability to consent to the study due to lack of capacity as documented by the referring physician.
References
Publications (1)
- DERIVEDPatel MI, Voskanyan M, Agajanian H, Agajanian R, Podnos Y, Milstein A. A Lay Health Worker-Led Symptom Intervention and Acute Care Use in Older Adults With Cancer: A Randomized Clinical Trial. JAMA. 2026 Feb 24;335(8):674-681. doi: 10.1001/jama.2025.23403. PMID 41468027