Clinical trial · Observational
Quality of Life After Rectal Cancer Surgery
Comparison of Quality of Life Outcomes Between Laparoscopic and Open Approach for Rectal Cancer Surgery
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Following colorectal surgery, many patients face a combination of physical and emotional problems for a long period of time. Symptoms such as pain, fatigue, and disturbed bowel and sexual function, as well as problems in social and role functioning, inevitably affect the patients' well-being. Therefore, evaluation of the self-reported quality of life (QoL) is becoming increasingly important in clinical trials. The investigators aimed to compare long term health related life quality (HRQoL) results of laparoscopic approach with open approach in patients with sphincter preserving resections for rectal cancer at a single-center.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Quality of Life | — | UNRESOLVED | — |
| Rectal Cancer | Malignant Rectal Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Laparoscopic Rectal cancer surgery | Procedure | — | UNRESOLVED |
| Open Rectal cancer surgery | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Open
- description
- Patients with open surgery for rectal cancer planned in our department.
- interventionNames
- Procedure: Open Rectal cancer surgery
- label
- Laparoscopic
- description
- Patients with laparoscopic surgery for rectal cancer planned in our department.
- interventionNames
- Procedure: Laparoscopic Rectal cancer surgery
Primary outcomes (11)
- measure
- Age
- timeFrame
- Before surgery
- description
- Years
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * patients who underwent surgery (laparoscopic or open) for rectal cancer in our department. Exclusion Criteria: * The patients whose all oncological treatments had not been completed at least 6 months ago * The patients with ASA IV score * The patients with previous abdominal surgery * The patients who had developed major surgical complications (such as anastomosis leakage, requiring re-laparotomy, evisceration) * The patients who underwent a new abdominal surgery except for stoma closure * The patients with local recurrence or distant metastases * The patients who still had a stoma * The patients who did not want to take part in the study * The patients who missed in the follow-up period
References
Publications (3)
- BACKGROUNDAndersson J, Angenete E, Gellerstedt M, Angeras U, Jess P, Rosenberg J, Furst A, Bonjer J, Haglind E. Health-related quality of life after laparoscopic and open surgery for rectal cancer in a randomized trial. Br J Surg. 2016 Nov;103(12):1746. doi: 10.1002/bjs.10280. Epub 2016 Jul 6. No abstract available. PMID 27801927
- BACKGROUNDD'Ambrosio G, Paganini AM, Balla A, Quaresima S, Ursi P, Bruzzone P, Picchetto A, Mattei FI, Lezoche E. Quality of life in non-early rectal cancer treated by neoadjuvant radio-chemotherapy and endoluminal loco-regional resection (ELRR) by transanal endoscopic microsurgery (TEM) versus laparoscopic total mesorectal excision. Surg Endosc. 2016 Feb;30(2):504-511. doi: 10.1007/s00464-015-4232-8. Epub 2015 Jun 5. PMID 26045097
- BACKGROUNDD'Ambrosio G, Picchetto A, Campo S, Palma R, Panetta C, De Laurentis F, La Rocca S, Lezoche E. Quality of life in patients with loco-regional rectal cancer after ELRR by TEM versus VLS TME after nChRT: long-term results. Surg Endosc. 2019 Mar;33(3):941-948. doi: 10.1007/s00464-018-6583-4. Epub 2018 Nov 12. PMID 30421081