Clinical trial · Interventional
A Single Center Study on Comparing the Different Function of EndoAngel in Improving the Quality of Colonscopy
A Prospective, Randomized, Single-blind, 2 × 2 Factorial Design Single Center Study Evaluating the Polyp Detection and Quality Monitoring Function of EndoAngel in Improving the Quality of Colonoscopy
NCT04453956CI-TRIAL-00047815unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
An artificial intelligence-based system, named EndoAngel,has been constructed previously,which has polyp detection and quality monitoring functions. This study aims to evaluate the two different functions of EndoAngle in improving adenoma detection rate.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Adenoma | Adenoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Colonoscopy without the assistance of EndoAngel's any function. | Diagnostic Test | — | UNRESOLVED |
| Colonoscopy with the assistance of EndoAngel's polyp detection function. | Diagnostic Test | — | UNRESOLVED |
| Colonoscopy with the assistance of EndoAngel's quality monitoring function. | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- type
- SHAM_COMPARATOR
- label
- Control group
- description
- Patients will receive colonoscopy without assistance of EndoAngel's any function.
- interventionNames
- Diagnostic Test: Colonoscopy without the assistance of EndoAngel's any function.
- type
- EXPERIMENTAL
- label
- Polyp detection function group
- description
- Patients will receive colonoscopy with the assistance of EndoAngel's polyp detection function.
- interventionNames
- Diagnostic Test: Colonoscopy with the assistance of EndoAngel's polyp detection function.
- type
- EXPERIMENTAL
- label
- Quality monitoring function group
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Male or female aged 18 years or above; 2. Colonoscopy is needed to further characterize gastrointestinal diseases; 3. Ability to read, understand and sign informed consent forms; 4. The researchers believe that the subjects can understand the process of the clinical study and are willing and able to complete all the study procedures and follow-up visits to cooperate with the study procedures. Exclusion Criteria: 1. Participated in other clinical trials, signed informed consent forms and followed up in other clinical trials; 2. Participate in a drug clinical trial and during the elution period of the trial or control drug; 3. Drug or alcohol abuse or mental disorder in the last 5 years; 4. Pregnant or lactating women; 5. Patients with multiple polyp syndrome; 6. Patients with a history of inflammatory bowel disease, colorectal cancer, or colorectal surgery; 7. Patients with known perforation or colonic obstruction; 8. Patients with a contraindication for biopsy; 9. The researchers did not consider the subjects suitable for colonoscopy; 10. The researchers determined that the subjects had high-risk diseases or other special conditions that were not appropriate for clinical trials.
References
Publications (1)
- DERIVEDYao L, Zhang L, Liu J, Zhou W, He C, Zhang J, Wu L, Wang H, Xu Y, Gong D, Xu M, Li X, Bai Y, Gong R, Sharma P, Yu H. Effect of an artificial intelligence-based quality improvement system on efficacy of a computer-aided detection system in colonoscopy: a four-group parallel study. Endoscopy. 2022 Aug;54(8):757-768. doi: 10.1055/a-1706-6174. Epub 2022 Feb 4. PMID 34823258