Clinical trial · Observational
Autonomic Reflexes During Intra-arterial Chemotherapy for Retinoblastoma
Cardiorespiratory Autonomic Reflexes During Superselective Ophthalmic Artery Chemotherapy for Retinoblastoma in Children: a Prospective Observational Study.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Prospective observational study in patients undergoing intra-arterial ophthalmic artery chemotherapy for the treatment of retinoblastoma. The main objective of the study is to evaluate the incidence of cardiorespiratory autonomic reflexes in these patients and to investigate the association between autonomic reflexes and perioperative clinical characteristics.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Chemotherapy Effect | — | UNRESOLVED | — |
| Retinoblastoma | Retinoblastoma | ONTOLOGY_EXACT | 0.98 |
| Retinoblastoma Bilateral | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Cardiorespiratory autonomic reflexes incidence
- timeFrame
- from the admission of the patient in the operating room until the end of the procedure (intra-arterial chemotherapy)
- description
- To evaluate the incidence of cardiorespiratory autonomic reflexes during intra-arterial chemotherapy of the ophthalmic artery in a child cancer center.
Secondary outcomes (1)
- measure
- Clinical background and autonomic reflexes occurence
- timeFrame
- from the admission of the patient in the operating room until the end of the procedure.
- description
- To evaluate the association between perioperative characteristics (both baseline and intraoperative characteristics) and the incidence of cardiorespiratory autonomic reflexes
Eligibility
Eligibility (as posted)
- Sex
- All
- Maximum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * All patients diagnosed with retinoblastoma and submitted to intra-arterial chemotherapy during the study period * Informed consent form signed and dated by legal guardian and investigator * Informed assent form signed by the patient if appropriate Exclusion Criteria: * Refusal of the patient or guardian to participate in the research project
References
Publications (0)
Data not yet available