Clinical trial · Observational
Prevalence of Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) Following Squamous Cell Carcinomas of the Oropharynx Treatment by Combined Chemoradiotherapy
NCT04440618CI-TRIAL-00049436COROSASunknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The study's aim is to determinate the prevalence of obstructive sleep apnea hypopnea syndrome after treatment by combined chemoradiotherapy in a locally advanced stages treated population of oropharyngeal cancer. Indeed, the level of knowledge about the consequences of oropharyngeal cancer treatment on sleep quality remains poor but the few studies published on the subject suggest an increased risk of development of OSAHS for these patients.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Obstructive Sleep Apnea-hypopnea | — | UNRESOLVED | — |
| Oropharyngeal Cancer | Malignant Oropharyngeal Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Prevalence of obstructive sleep apnea hypopnea syndrome after treatment by combined chemoradiotherapy.
- timeFrame
- Day 28
- description
- Number of patients with obstructive sleep apnea hypopnea syndrome after treatment combined chemoradiotherapy.
Secondary outcomes (1)
- measure
- Severity of OSAHS as a function of the post-therapeutic delay.
- timeFrame
- Day 28
- description
- Value of the AHI as a function of the post-therapeutic delay which corresponds to the delay compared to the end of the curative treatment carried out for squamous cell carcinoma of the oropharynx. It is obtained after the inclusion visit and the realization of the polygraphy with the IAH score. OSAHS is mild (if IAH ≥ 5 / h and \<15 / h), moderate (if IAH ≥ 15 / h and ≤ 30 / h) or severe (if IAH\> 30 / h)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age\> 18 years old * Performance Status 0-2 * Squamous cell carcinoma of the oropharynx treated with concomitant chemoradiotherapy * Treatment termination time greater than 6 months at inclusion * Tumor classification (American Joint Committee on Cancer 8th) T2-T4 N0-N3 * Patient in complete remission at inclusion * patient's consent's obtained after information Exclusion Criteria: * Previous treatment for upper aerodigestive tract cancer * Incomplete radiotherapyTreatment * Neurological pathology wich may affect the functions of the upper aerodigestive tract * Pregnant or breastfeeding woman * Unweaned alcoholism * Tracheotomized patient at the time of the study * Patient under protection: subjects with guardianship or under law protection * No health insurance coverage
References
Publications (0)
Data not yet available
No reference posted for this study.