Clinical trial · Observational

Influence of Positive Margins on Tumour Recurrence and Overall Survival After Gastrectomy for Gastric Cancer

NCT04439812CI-TRIAL-00045613completedClinicalTrials.gov clinicaltrialsPublishedExplore in graph →

Summary

Brief summary (as posted)

Incidence of positive surgical margins after curative gastrectomy ranges from 1% to 20%. It has been suggested that positive surgical margins is an adverse prognosis factor, with a higher local recurrence and worse overall survival (OS). However, the management of these patients remains unclear.

Conditions

Conditions (1)

Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.

Condition (as posted)	Mapped entity	Match	Confidence
Stomach Neoplasms	Gastric Neoplasm	ALIAS	0.90

Interventions

Interventions (1)

Intervention	Type	Mapped drug	Match
Observation	Other	—	UNRESOLVED

Design

Arms and outcomes

Arms (2)

label
R=0
description
Patients without positive margins after gastrectomy for gastric cancer
interventionNames
1. Other: Observation
label
R=1
description
Patients with positive margins after gastrectomy for gastric cancer
interventionNames
1. Other: Observation

Primary outcomes (1)

measure
evaluate the influence of positive margins on the tumour's recurrence and OS after gastrectomy for GC
timeFrame
8 years

Secondary outcomes (1)

measure

Eligibility

Eligibility (as posted)

Sex: All

Show eligibility criteria text

Inclusion Criteria:

* all consecutive patients who underwent an oncological gastrectomy due to gastric cancer, between January 2010 and December 2018 at Ramon y Cajal University Hospital.

Exclusion Criteria:

* distant disease (including patients with positive cytology), early postoperative mortality (within 30 days after surgery) and follow-up data not available. Resections in patients with palliative intent were also excluded.

References

Publications (0)

Data not yet available

No reference posted for this study.