Clinical trial · Observational
A Single-cell Transcriptome Study in Patients With Non-Hodgkin's Lymphoma
NCT04434833CI-TRIAL-00045823unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Using single-cell RNA sequencing, this study will explore the heterogeneity of lymphoma inside and outside the lymph node, identify tumor specific molecular markers and cell subgroups, explore the differences in tumor microenvironment composition, and provide a basis for diagnosis and precision treatment.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Non Hodgkin Lymphoma | Non-Hodgkin Lymphoma | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (3)
- label
- Extra nodal diseases
- description
- Patients with both lymph node and extra nodal involvement.
- label
- Target drugs
- description
- Patients enrolled in clinical trials of novel target drugs.
- label
- Relapse
- description
- Patients with high risk of relapse.
Primary outcomes (4)
- measure
- Extra nodal involvement
- timeFrame
- At enrollment
- description
- Clinical diagnosis of lymphoma invasion in extra nodal organs with or without pathological confirmation
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 14 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with pathological confirmed diagnosis of non-Hodgkin's lymphomas. * Patients with both lymph node and extra nodal involvement, or patients at high risk of relapse, or patients receiving a novel target drug treatment.
References
Publications (0)
Data not yet available
No reference posted for this study.