Clinical trial · Observational
Nailfold Capillaroscopy Evaluation in Cushing Syndrome Patients
Skin Microcirculation Evaluation With Nailfold Capillaroscopy in Cushing's Syndrome Patients
NCT04433819CI-TRIAL-00045563unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This cross-sectional, single-center study will assess the microvascular function using a nailfold video-capillaroscopy in patients with endogenous Cushing syndrome.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cushing Syndrome | — | UNRESOLVED | — |
| Hypercortisolism | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (2)
- label
- Cushing syndrome
- description
- Male and female patients diagnosed as Cushing syndrome caused by ACTH-producing pituitary adenoma or cortisol producing adrenal adenoma
- label
- Controls
- description
- Healthy controls matched for age, gender, and body mass index
Primary outcomes (3)
- measure
- Nailfold capillary number of tortuous loops
- timeFrame
- 6 months
- description
- Nailfold capillary area changes
- measure
- Nailfold capillary area number of meandering capillaries
- timeFrame
- 6 months
- description
- Nailfold capillary area changes
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Male and female patients diagnosed as Cushing syndrome (CS) caused by ACTH-producing pituitary adenoma or cortisol producing adrenal adenoma * Age between 18 and 70 years Exclusion Criteria: * Chronic glucocorticoid use * CS caused by ectopic ACTH producing tumors * CS caused by adrenocortical carcinoma * Pseudo CS * Patients with Raynaud phenomenon * Patients with collagen tissue disease * Patients who use drugs that affect the metabolism of fibrinolysis (such as oral contraceptives) * Employees at work at risk of microtrauma (such as gardeners, farmers) * Skin diseases with nail fold involvement (such as dermatitis, psoriasis)
References
Publications (0)
Data not yet available
No reference posted for this study.