Clinical trial · Interventional
Magnesium Sulphate to Bupivicaine in Serratus Anterior Plane Block in Modified Radical Mastectomy
Effectiveness of Adding Magnesium Sulphate to Bupivicaine in Ultrasound Guided Serratus Anterior Plane Block in Patients Undergoing Modified Radical Mastectomy
NCT04429893CI-TRIAL-00060035unknownPhase 2 / Phase 3ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Modified radical mastectomy may be associated with severe post-operative pain, leading to chronic pain syndrome which usually requires optimal perioperative pain management.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer Breast | Breast Neoplasm | PROBABILISTIC | 0.70 |
| Chronic Pain Syndrome | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| bupivicaine | Drug | — | UNRESOLVED |
| magnesium sulphate | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Group BM
- description
- The patients will receive 20 ml of 0.5% bupivacaine plus 150 mg magnesium sulphate in 0.9% normal saline with a total volume of 25 ml.
- interventionNames
- Drug: magnesium sulphate
- Drug: bupivicaine
- type
- ACTIVE_COMPARATOR
- label
- Group B
- description
- The patients will receive 20 ml of 0.5% bupivacaine plus 5 ml 0.9% normal saline with total volume 25 ml
- interventionNames
- Drug: bupivicaine
Primary outcomes (1)
- measure
- assessment of the pain intensity
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 20 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * adult female patients * American Society Of Anesthesiologists (ASA) class I or II * scheduled for elective unilateral modified radical mastectomy Exclusion Criteria * patient refusal * bilateral breast surgery * coagulation disorders * body mass index\> 35 * allergy to local anaesthetics or magnesium sulphate * severe respiratory or cardiac disorders * pre-existing neurological deficits * liver or renal insufficiency
References
Publications (0)
Data not yet available
No reference posted for this study.