Clinical trial · Observational
A Comparative Study of Mammography and Ultrasound for Breast Cancer Screening and Early Diagnosis
NCT04429269CI-TRIAL-00045872MUSDunknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Improving the early diagnosis of breast cancer can reduce mortality. With mammography as the main tool for screening early breast cancer, the characteristics of dense breast and young onset of disease in Chinese women lowers the efficiency. The aim of this prospective study was to compare which method, x-ray or ultrasound, is more appropriate for screening and early diagnosis of breast cancer in Chinese women.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer Diagnosis | — | UNRESOLVED | — |
| Breast Cancer Screening | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| mammography and ultrasound screening | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- mammography and ultrasound
- description
- mammography and ultrasound screening
- interventionNames
- Diagnostic Test: mammography and ultrasound screening
Primary outcomes (1)
- measure
- screening yield
- timeFrame
- 3 years
- description
- The sensitivity, specificity, positive predictive value, and negative predictive value of the screening methods.
Secondary outcomes (1)
- measure
- cost-effectiveness
- timeFrame
- 3 years
- description
- The cost-effectiveness of each screening modality to detect one case of breast cancer
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 35 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Informed consent, subjects 35-70 years old, asymptomatic, able to undergo ultrasound and x-ray Exclusion Criteria: * Localized breast erythema and ulceration, pregnancy, lactation, after previous breast implantation, already pathologically definite breast cancer patients
References
Publications (2)
- DERIVEDWang Y, Li Y, Qu Y, Zhou Y, Sun Q, Shen S. Clinical and imaging characteristics of intraductal papillary neoplasms of the breast: a prospective trial. Discov Oncol. 2024 Dec 23;15(1):831. doi: 10.1007/s12672-024-01681-y. PMID 39715848
- DERIVEDWang Y, Li Y, Song Y, Chen C, Wang Z, Li L, Liu M, Liu G, Xu Y, Zhou Y, Sun Q, Shen S. Comparison of ultrasound and mammography for early diagnosis of breast cancer among Chinese women with suspected breast lesions: A prospective trial. Thorac Cancer. 2022 Nov;13(22):3145-3151. doi: 10.1111/1759-7714.14666. Epub 2022 Sep 30. PMID 36177910