Clinical trial · Observational
Therapeutic Recommendations For The Treatment Of Children With A Retinoblastoma
NCT04425434CI-TRIAL-00104330GFARB12019recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
As the survival of children with retinoblastoma in high income countries is higher than 95% including the bilateral forms this study hopes to improve the outcome in low income countries in Africa by improving early diagnosis and early implementation of this protocol of therapeutic recommendations for treatment.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Retinoblastoma | Retinoblastoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| OBSERVATIONAL | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (5)
- measure
- Number of cases with retinoblastoma in each participating hospital.
- timeFrame
- 10 years
- description
- Evaluation of the number of cases registered .
- measure
- Number of cases with stage 2 disease
- timeFrame
- 10 years
- description
- Evaluation of the number of cases registered with stage 2 disease.
- measure
- Feasibility of these therapeutic recommendations in an African setting
- timeFrame
- 10 years
- description
- Evaluate the application of these therapeutic recommendations
- measure
- Evaluating the treatment given.
Eligibility
Eligibility (as posted)
- Sex
- All
- Maximum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Unilateral intraocular Retinoblastoma (RB) * Unilateral extraocular intraorbital (RB) * Bilateral intraocular (RB) * bilateral intraocular (RB) on one side and extraocular but intraorbital on the other side. Exclusion Criteria: * Externalized tumor mass * massive extension to optic nerve up to optical channeltumor * intracranial extension leptomeninges * cerebral parenchyma * extension to regional lymph nodes and/or remote metastases. * cerebrospinal fluid involvement. * Trilateral RB * Incapacity to followed the whole treatement.
References
Publications (0)
Data not yet available
No reference posted for this study.