Clinical trial · Observational
Hyperlactatemia During and After Tumorcraniotomy
Elevated Serum-lactate in Patients With Brain Tumor During and After Elective Craniotomy: an Observational Clinical Study of Postoperative Patient Outcome.
NCT04410315CI-TRIAL-00060383completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study aims to investigate the association between hyperlactatemia and neurological disability, length-of-stay and mortality in patients who undergo tumorcraniotomy. The risk factors that induce lactat accumulation will also be explored.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Anesthesia | — | UNRESOLVED | — |
| Brain Tumor | Brain Neoplasm | ALIAS | 0.90 |
| Hyperlactatemia | — | UNRESOLVED | — |
| Surgery | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Serum-lactate < 2,2 mmol/L | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Tumorcraniotomy patients
- interventionNames
- Other: Serum-lactate < 2,2 mmol/L
- Other: Serum-lactate >/= 2,2 mmol/L
Primary outcomes (1)
- measure
- Neurological disability
- timeFrame
- Change from baseline mRS at 30 days after surgery
- description
- Modified Rankin Scale (Scoring 0-6, high scores meaning worse outcome)
Secondary outcomes (2)
- measure
- Length of hospital stay
- timeFrame
- 1 year
- description
- In days from admission to discharge.
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age \>/= 18 years * Must undergo elective tumor craniotomy * Understand oral and written Danish Exclusion Criteria: * Adults with incapacity * Stereotactic biopsy * Lack of informed and signed consent to participate in study
References
Publications (0)
Data not yet available
No reference posted for this study.