Clinical trial · Interventional
Shear Wave Elastography of Rectal Adenomas and Cancer
NCT04409990CI-TRIAL-00061267completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The diagnosis of rectal lesions is a challenging task, and the accuracy of the primary staging is important preoperatively. A relatively novel technology makes it possible to measure the tissue stiffness during endorectal ultrasonography. The purpose of this study is to evaluate the diagnostic value of Shear Wave Elastography (SWE). The hypothesis is that the tissue stiffness is higher in malignant tissue than in benign lesions.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Elasticity Imaging Techniques | — | UNRESOLVED | — |
| Rectal Neoplasms | Rectal Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Shear Wave Elastography | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- OTHER
- label
- Shear Wave Elastography
- description
- SWE value measurement will be added during the ERUS examination.
- interventionNames
- Diagnostic Test: Shear Wave Elastography
Primary outcomes (1)
- measure
- SWE accuracy
- timeFrame
- 1 month
- description
- The accuracy of SWE value as compared with the histopathology report
Secondary outcomes (1)
- measure
- SWE and ADC measurement
- timeFrame
- 1 week
- description
- The correlation between ERUS SWE and MRI ADC value
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * Adults above 18 years of age * Rectal lesions discovered during endoscopy * Lesions located no more than 15 cm above the anal verge Exclusion Criteria: * Non-eligibility for MRI (e.g. claustrophobia, implants) * Preoperative radiotherapy and/or chemotherapy
References
Publications (1)
- BACKGROUNDLi T, Lu M, Li Y, Li J, Hu Z, Li X, Cheng X, Jiang J, Tan B. Quantitative Elastography of Rectal Lesions: The Value ofShear Wave Elastography in Identifying Benign and Malignant Rectal Lesions. Ultrasound Med Biol. 2019 Jan;45(1):85-92. doi: 10.1016/j.ultrasmedbio.2018.09.008. Epub 2018 Oct 17. PMID 30342780