Clinical trial · Interventional
Enhanced Supportive Care for Advanced Cancer Patients: Evaluation of Standardized Care Pathway
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to evaluate the efficacy of the standardized care pathway which provides enhanced supportive care for patients with advanced cancer. A pilot study (single arm pre-post test) will be conducted to evaluate feasibility of applying standardized care pathway to provide enhanced supportive care. A Randomized Controlled Trial will be conducted by randomly allocating participants in a 1:1 ratio to intervention arm (receiving enhanced supportive care according to the standardized care pathway) or control arm (receiving usual care: symptom monitoring only). Participants in the intervention arm will receive enhanced supportive care consisted of symptom management and coping enhancement counseling for 5 times. Data from advanced cancer patients will be collected at baseline (before start of chemotherapy), during chemotherapy (intervention arm), at the visit for cycle 5 of chemotherapy, at 6 month, and at 12 month Data from caregivers will be collected at baseline, 3 month, and 6 month. Primary outcomes will be measured as advanced cancer patients' symptom, coping and quality of life.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Advanced Cancer | Malignant Neoplasm | CURATED_BROADER | 0.78 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Control group with usual care | Other | — | UNRESOLVED |
| Enhanced supportive care based on standardized care pathway | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- A
- description
- Experimental group with application of the standardized care pathways and symptom management education
- interventionNames
- Other: Enhanced supportive care based on standardized care pathway
- type
- OTHER
- label
- B
- description
- Control group with usual care (symptom monitoring only)
- interventionNames
- Other: Control group with usual care
Primary outcomes (3)
- measure
- Symptom measured by the ESAS (Edmonton Symptom Assessment Scale + 5 additional symptoms)
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 19 Years
Show eligibility criteria text
Inclusion Criteria: * adult (age \>=19 years old), * cancer patients and their family * ECOG =\<2 Exclusion Criteria: * patients with cognitive or psychiatric issue
References
Publications (3)
- DERIVEDHong B, Choi YY, Lee HS, Lee J. Mechanisms underlying the effect of nurse-led enhanced supportive care for advanced cancer patients: A mediation analysis of randomized controlled trial data. Eur J Oncol Nurs. 2026 Jun;82:103186. doi: 10.1016/j.ejon.2026.103186. Epub 2026 Apr 2. PMID 41946322
- DERIVEDChoi YY, Hong B, Rha SY, Cho S, Lee HS, Lee J. The effect of nurse-led enhanced supportive care as an early primary palliative care approach for patients with advanced cancer: A randomized controlled trial. Int J Nurs Stud. 2025 Aug;168:105102. doi: 10.1016/j.ijnurstu.2025.105102. Epub 2025 May 1. PMID 40378811
- DERIVEDChoi YY, Rha SY, Cho S, Lee HS, Hong B, Lee J. Enhanced supportive care for advanced cancer patients: study protocol for a randomized controlled trial. BMC Nurs. 2022 Dec 2;21(1):338. doi: 10.1186/s12912-022-01097-5. PMID 36461000