Clinical trial · Interventional
Effects of Periodized and Autoregulated Resistance Training in Haematological Cancer Patients During the Treatent.
Effects of Periodized and Autoregulated Resistance Training Programs in Haematological Cancer Patients Undergoing High-dose Chemotherapy and Hematopoietic Stem Cell Transplantation: A Randomized, Controlled Clinical Trial.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Several clinical trials have demonstrated the positive impact of physical functioning and fatigue in patients who received training programs during the myeloablative chemotherapy with stem cell transplantation. However, the heterogeneity among the forms of physical activity results in moderate to very low evidence available about benefits of physical exercise. In this randomized and controlled clinical trial, we will study the effects on physical performance and fatigue of periodic resistance training programs, with an autoregulated approach within a non-linear model, based on the individual patient response to cancer treatment.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Periodic Resistance Training Program Leukemia | Other | — | UNRESOLVED |
| Periodic Resistance Training Program Lymphoma | Other | — | UNRESOLVED |
| Standard protocol Leukemia | Other | — | UNRESOLVED |
| Standard protocol Lymphoma | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- type
- ACTIVE_COMPARATOR
- label
- Leukemia Control Group
- description
- In this group the exercise program will be based on the standard protocol of physical therapy.
- interventionNames
- Other: Standard protocol Leukemia
- type
- EXPERIMENTAL
- label
- Leukemia Experimental Group
- description
- In this group the exercise program will be based on a periodic resistance training program, with an autoregulated approach within a non-linear model, based on the individual's patient daily response.
- interventionNames
- Other: Periodic Resistance Training Program Leukemia
- type
- ACTIVE_COMPARATOR
- label
- Lymphoma Control Group
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 64 Years
Show eligibility criteria text
Inclusion Criteria: * Patients clinically diagnosed with Leukemia or Lymphoma, in the first or second line of treatment, undergoing high-dose chemotherapy, with or without hematopoietic stem cell transplantation; * Neurological and cognitive functions preserved; * Physical conditions that enable participation in physical rehabilitation. Exclusion Criteria: * Clinical Complications that contraindicate physical therapy exercises, including the practice of cycle ergometer and resistance exercises; * Previous musculoskeletal alteration that interferes in physical performance evaluation tests; * Recent cardiovascular or pulmonary disease; * Psychiatric or neurological disorder; * Inability to walk on its own or presence of bone metastasis; * Adherence on less than 50% of the total sessions of the study.
References
Publications (0)
Data not yet available