Clinical trial · Interventional
Red Bull Energy Drink Intake After Autologous Microsurgical Breast Reconstruction
Flying High - Exploring the Effect of Red Bull Energy Drink Intake After Autologous Microsurgical Breast Reconstruction
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The success rate of autologous microsurgical breast reconstruction depends on adequate intraoperative and postoperative flap perfusion. Perfusion is optimized intraoperatively by a full hyperdynamic circulation and maintenance of a normal body temperature. Additional safe and simple postoperative measures to guarantee adequate perfusion pressure would be desirable. Recently, the effect of Red Bull® Energy Drink on cardiovascular and renal function, pain tolerance as well as performance has been studied in clinical trials involving healthy volunteers and athletes. Notably, an increase in blood pressure, heart rate, improved endothelial function and reduced pain perception have been observed. A better understanding of its effects in patients undergoing autologous microsurgical breast surgery would be of great value. When ingested in standard amounts, Red Bull® Energy Drink has been shown to be a safe beverage without notable side effects. The investigators prospectively study the effect of postoperative oral ingestion of Red Bull® Energy Drink on perfusion-related variables and patient recovery after autologous microsurgical breast reconstruction.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Red Bull Energy Drink | Dietary Supplement | — | UNRESOLVED |
| Still water | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Intervention group
- description
- This group is administered a total of 750 ml Red Bull® Energy Drink at defined time-intervals.
- interventionNames
- Dietary Supplement: Red Bull Energy Drink
- type
- PLACEBO_COMPARATOR
- label
- Placebo group
- description
- This group is administered a total of 750 ml still water at defined time-intervals.
- interventionNames
- Other: Still water
Primary outcomes (1)
- measure
- Blood pressure
- timeFrame
- Until 2 hours after last drink ingestion
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: 1. Indication: Patients undergoing unilateral autologous microsurgical breast reconstruction by Prof. Dr. med. Jian Farhadi, Dr. med. Alessia Lardi or Dr. med. Doris Babst 2. Female participants ≥ 18 and ≤ 70 years of age 3. Able to give written informed consent prior to participation in the study, which includes ability to comply with the requirements and restrictions listed in the consent form. Exclusion Criteria: 1. History of arterial hypertension\* 2. History of cardiac rhythm disorder\* 3. History of Diabetes mellitus\* 4. History of gastric or duodenal ulcer\* 5. History of hyperthyroidism or hypothyroidism\* 6. Current use of antihypertensive drugs, antiarrhythmic drugs, thyroid hormones (e.g. Euthyrox)\* 7. Allergy or intolerance to component of Red Bull® Energy Drink 8. Not fulfilling inclusion criteria. \* as diagnosed by the GP in the referral letter
References
Publications (1)
- DERIVEDSpeck NE, Michalak M, Dreier K, Babst D, Lardi AM, Farhadi J. Effect of the Red Bull Energy Drink on Perfusion-Related Variables in Women Undergoing Microsurgical Breast Reconstruction: Protocol and Analysis Plan for a Prospective, Multicenter Randomized Controlled Trial. JMIR Res Protoc. 2023 May 9;12:e38487. doi: 10.2196/38487. PMID 37159251