Clinical trial · Interventional
Effect of Radioiodine Therapy on Ovarian Reserve in Female Patients With Differentiated Thyroid Cancer
NCT04396158CI-TRIAL-00045247unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Thyroid carcinoma is the most common endocrine malignancy. Surgery is the standard therapeutic approach for patients with differentiated thyroid carcinoma (DTC), followed by radioiodine (RAI) therapy if indicated. For women with DTC, the effects of RAI therapy on gonadal and reproductive function are an important consideration. This study aimed to evaluate the effects of RAI therapy on ovarian function.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Ovarian Insufficiency | — | UNRESOLVED | — |
| Radiation Exposure | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| radioactive iodine | Radiation | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- intervention
- interventionNames
- Radiation: radioactive iodine
Primary outcomes (1)
- measure
- Level of anti-Müllerian (AMH) hormone
- timeFrame
- 6 months
- description
- Level of anti-Müllerian (AMH) hormone in female patients before and after radioactive iodine therapy.
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 15 Years
- Maximum age
- 45 Years
Show eligibility criteria text
Inclusion Criteria: * Female patient in childbearing period. * Female patient with differentiated thyroid carcinoma. * Underwent thyroidectomy. * Candidate for radioactive iodine therapy. Exclusion Criteria: * • Male patients. * Postmenopausal female patients. * Female patients with undifferentiated thyroid carcinoma. * Pregnant female patients. * Lactating female patients.
References
Publications (0)
Data not yet available
No reference posted for this study.