Clinical trial · Observational
Para Aortic Lymphadenectomy : Always ?
Assesment of Paraaortic Lymphadenectomy in Locally Advanced Cervical Cancer, When no Pathologic Pelvic Lymph Node on PET/CT: Retrospective Study.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Cervical cancer affects more than 3000 new cases per year in France. The treatment of stage IB3 to IVA cervical cancer is based on concomitant radio-chemotherapy. The irradiation volumes are based, according to current recommendations, on imaging examinations and / or on the results of a laparoscopic Para-aortic lymphadenectomy (PAL). There is some risk of false negatif with the PET/CT. For this reason, most of the time, PAL is offered when there is no pathological paraaortic lymph node on PET/CT. The investigators suppose that this staging surgery could be avoid when no pathological pelvic nodes are identified on PET/CT. The investigators use a retrospective study, to analyse histological report of systematic PAL, comparing to results of pre-operative PET/CT.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cervical Cancer | Malignant Cervical Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Para Aortic Lymphadenectomy (PAL) by laparoscopy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Patients with locally advanced cervical cancer
- description
- Patients with locally advanced cervical cancer, who had undergone a PAL
- interventionNames
- Procedure: Para Aortic Lymphadenectomy (PAL) by laparoscopy
Primary outcomes (1)
- measure
- negative predictive value of PET/CT on para aortic nodes when no pathological pelvic nodes.
- timeFrame
- 1 day
- description
- negative predictive value of PET/CT on para aortic nodes when no pathological pelvic nodes. The intraoperative 3D optical scan gives the tumor localization obtained by radioguided occult lesion localization thanks to pen marking left by the surgeon. The comparison is done by superimposing both acquisitions.
Secondary outcomes (1)
- measure
- morbidity of PAL
- timeFrame
- 1 day
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion criteria: \- Patients with : * locally advanced cervical cancer, * who undergone PAL * with pre operative PET CT, between January 2015 and december 2019 Exclusion criteria: \- patients aged under 18
References
Publications (0)
Data not yet available