Clinical trial · Interventional
Prevention of Breast Cancer-related Lymphedma With Tacrolimus
NCT04390685CI-TRIAL-00052444BCRL-TACROunknownPhase 1 / Phase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Breast cancer-related lymphedema is one of the most common and feared consequences of breast cancer treatment. Tacrolimus ointment may prevent lymphedema by inhibition of CD4+T cells.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lymphedema | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Tacrolimus ointment | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Tacrolimus ointment
- description
- Apply whole arm, in a thin layer, once daily for one year
- interventionNames
- Drug: Tacrolimus ointment
- type
- NO_INTERVENTION
- label
- Control
Primary outcomes (1)
- measure
- Lymphedema
- timeFrame
- 1 year
- description
- Arm size change \>= 10% using water displacement
Secondary outcomes (5)
- measure
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Female * Breast cancer with planned ALND * postmenopausal or use of contraceptives * good general health condition * read and understand Danish Exclusion Criteria: * Pregnant, breastfeeding it wishing to conceive with the next year * bilateral breast cancer * known allergy to tacrolimus or macrolides * known lymphedema * other malignant disease apart from keratinocyte cancer * in medical treatment for diabetes mellitus * known psychiatric condition which may influence participation * known renal or hepatic function
References
Publications (0)
Data not yet available
No reference posted for this study.