Clinical trial · Interventional
Promoting Genetic Counseling Among African American Women With a Family History of Breast Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
In the United States, carriers of hereditary genetic mutations have up to an 85% risk of developing breast cancer compared to 12% in the general population. Overall uptake of genetic services is generally low, particularly among high-risk African American (AA) women, who carry a disproportionate burden of breast cancer mortality. Further, although testing close relatives of individuals who test positive for a pathogenic variant might curtail breast cancer disparities attributable to hereditary risk, it is unclear how counseled or tested individuals influence their social and familial networks. Using a randomized control trial design, the objective of this research project is to test the effectiveness of a culturally targeted video, previously developed by our research team, on promoting genetic counseling attendance among AA women determined to be at high risk for breast cancer through cancer genetic risk assessment in a clinical setting. This study will also test how psychosocial factors (knowledge, intrinsic motivation, risk perception, and distress) impact the relationships between intervention exposures (video versus brochure) and compare the impact of intervention exposures on diffusion of knowledge about genetic counseling through social network analysis.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| High Risk for Breast Cancer | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Decision aid video | Behavioral | — | UNRESOLVED |
| Genetic counseling informational brochure | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Decision aid video
- description
- Participants receiving the intervention will complete a pretest, watch the decision aid video, and complete posttest via tablet computer facilitated by Patient Navigators.
- interventionNames
- Behavioral: Decision aid video
- type
- ACTIVE_COMPARATOR
- label
- Genetic counseling informational brochure
- description
- Participants receiving the control will complete pretest, review a genetic counseling brochure with the Patient Navigators, and complete posttest via tablet computer facilitated by a Patient Navigator.
- interventionNames
- Behavioral: Genetic counseling informational brochure
Primary outcomes (1)
- measure
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 25 Years
Show eligibility criteria text
Inclusion Criteria: 1. Are female 2. Identify as African American 3. Are age 25 or older 4. Speak and understand English 5. Completed a cancer genetic risk assessment (CGRA) as part of clinic intake 6. Are classified as high risk for developing breast cancer per CGRA 7. Have not previously received genetic counseling Exclusion Criteria: 1. Are not female 2. Do not identify as African American 3. Are age 24 or younger 4. Do not speak and understand English 5. Did not complete a cancer genetic risk assessment (CGRA) as part of clinic intake 6. Are not classified as high risk for developing breast cancer per CGRA 7. Have previously received genetic counseling
References
Publications (0)
Data not yet available