Clinical trial · Interventional
Utility of Indocyanine Green Fluorescence in Endoscopic Sinonasal and Skull Base Surgery
The Utility of Indocyanine Green Fluorescence in Endoscopic Sinonasal and Skull Base Surgery - A Prospective Case-Series and Feasibility Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The endoscope is a device placed into the nasal cavity to remove chronic sinus disease or tumor or create access into the skullbase for extensive tumor removal. Indocyanine Green (ICG) is a dye that is injected through an intravenous site and is used to light up vasculature and margins of a tumor during surgery. This helps avoid damage to important vasculature and obtain clear margins during surgery. This study aims to further assess the utility of ICG when operating within the nasal cavity or skullbase.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Chronic Sinusitis | — | UNRESOLVED | — |
| Posterior Epistaxis | — | UNRESOLVED | — |
| Skull Base Neoplasms | Skull Base Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Tumor of Nasal Sinus | Paranasal Sinus Neoplasm | PROBABILISTIC | 0.70 |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Endoscopic Sinus Surgery | Procedure | — | UNRESOLVED |
| Posterior Epistaxis Management (SPA Ligation) | Procedure | — | UNRESOLVED |
| Sinonasal Benign or Malignant Tumor Resection | Procedure | — | UNRESOLVED |
| Skull Base Surgery (Assessment of Nasoseptal Flap) | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- type
- OTHER
- label
- Sinus Tumor Resection
- description
- Those who are undergoing endoscopic sinonasal surgery for benign and malignant tumor removal.
- interventionNames
- Procedure: Sinonasal Benign or Malignant Tumor Resection
- type
- OTHER
- label
- Skull Base Surgery
- description
- Those who are receiving Endoscopic Skull Base Surgery (ESBS) for minimally-invasive access for removal of skull base tumors, most commonly for ones of pituitary origin.
- interventionNames
- Procedure: Skull Base Surgery (Assessment of Nasoseptal Flap)
- type
- OTHER
- label
- Endoscopic Sinus Surgery
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 19 Years
Show eligibility criteria text
Inclusion Criteria: * All patients undergoing skull base surgery with nasoseptal flap reconstruction. * All patients undergoing endoscopic sinonasal surgery for benign and malignant tumor removal. * All patients undergoing endoscopic sinus surgery for chronic rhinosinusitis (CRS) with or without polyposis. * All patients undergoing surgical intervention for posterior epistaxis. Exclusion Criteria: * Patients less than 18 years of age * Patients whom are currently pregnant * Patients with allergies to sodium iodide or shellfish * Patients with previous anaphylactic reaction to ICG
References
Publications (0)
Data not yet available