Clinical trial · Interventional
Study of an eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Predisposition in Metastatic Cancer Patients
A Randomized Study of an eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Predisposition in Metastatic Breast, Ovarian, Prostate and Pancreatic Cancer Patients
NCT04353973CI-TRIAL-00092770eReachcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study aims to determine if web-based eHealth delivery of pre-test and/or post-test counseling in cancer patients and/or those at risk for cancer can provide equal or improved cognitive and affective outcomes when compared to the standard of care delivery model.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Post-Test Intervention | Other | — | UNRESOLVED |
| Pre-Test Intervention | Other | — | UNRESOLVED |
| Standard of Care | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- type
- EXPERIMENTAL
- label
- ARM A
- description
- Visit 1/Pre-Test Session - Standard-of-Care Pre-Test Counseling with a genetic counselor either in-person or by remote services (Telephone or Video Conferencing). Visit 2/Disclosure Session - Standard-of-Care Post-Test Counseling with a genetic counselor either in-person or by remote services (Telephone or Video Conferencing).
- interventionNames
- Other: Standard of Care
- type
- EXPERIMENTAL
- label
- ARM B
- description
- Visit 1/Pre-Test Session - Standard-of-Care Pre-Test Counseling with a genetic counselor either in-person or by remote services (Telephone or Video Conferencing). Visit 2/Disclosure Session - Self-directed web-based eHealth result disclosure intervention.
- interventionNames
- Other: Standard of Care
- Other: Post-Test Intervention
- type
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * 18 years of age or older * Speak and understand English * Male or Female * A personal history of one or more of the following: * metastatic breast cancer * advanced ovarian cancer (Stage III-IV) * metastatic pancreatic cancer * metastatic prostate cancer * Naive to previous cancer germline genetic testing Exclusion Criteria: * Communication difficulties such as: * Uncorrected or uncompensated hearing and/or vision impairment * Uncorrected or uncompensated speech defects * Uncontrolled psychiatric/mental condition or severe physical, neurological or cognitive deficits rendering individual unable to understand study goals and tasks
References
Publications (1)
- DERIVEDLee KT, McLeod B, Egleston B, Brown S, Howe S, Fetzer D, Gutstein L, Cacioppo C, Clark D, Domchek SM, Ebrahimzadeh J, Falcone D, Ofidis D, Griffin H, Mim R, Hernandez S, Fleisher L, Karpink K, Selmani E, Tahsin A, Wagner L, Weinberg M, Yi-Wen K, Wood E, Bradbury AR. An eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Predisposition in Patients With Metastatic Cancers: Protocol for a Randomized Trial. JMIR Res Protoc. 2025 Aug 25;14:e72515. doi: 10.2196/72515. PMID 40853717