Clinical trial · Observational
Surgical-Site Infection After Laparoscopic Right Colectomy
Surgical-Site Infection After Laparoscopic Right Colectomy: A Cohort Study Comparing Intracorporeal Anastomosis in Front of Extracorporeal Anastomosis
NCT04350203CI-TRIAL-00044706completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Laparoscopic right colectomy with intracorporeal anastomosis seems to be associated with several short-term benefits. It could reduce the postoperative infection rate and shorten the hospital stay. This study aimed to evaluate the postoperative surgical site infection (SSI) rate after laparoscopic right hemicolectomy with intracorporeal anastomosis, compared to extracorporeal anastomoses.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Surgical Site Infection | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Laparoscopic right colectomy with extracorporeal anastomosis (EA) | Procedure | — | UNRESOLVED |
| Laparoscopic right colectomy with intracorporeal anastomosis (IA) | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Intracorporeal Anatomosis (IA)
- description
- Laparoscopic Right colectomy with intracorporeal (IA) side-to-side isoperistaltic anastomosis
- interventionNames
- Procedure: Laparoscopic right colectomy with intracorporeal anastomosis (IA)
- label
- Extracorporeal Anastomosis (EA)
- description
- Patients submitted to a Laparoscopic Right Colectomy with extracorporeal anastomosis (EA)
- interventionNames
- Procedure: Laparoscopic right colectomy with extracorporeal anastomosis (EA)
Primary outcomes (3)
- measure
- Anastomotic leak rate
- timeFrame
- 30 days
- description
- percentage of clinical anastomotic leak leading to an intervention
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * patients over 18 years candidates for scheduled surgery with curative intention to resect a benign or malignant neoplasm of the right colon Exclusion Criteria: * stage IV disease (distant metastatic or intraabdominal disseminated disease that contraindicates surgery with curative intention) * emergency operation for complicated disease * medical contraindication for general anesthesia * pregnancy * chronic renal insufficiency requiring dialysis * or patient refusal and/or absence of informed consent.
References
Publications (4)
- BACKGROUNDPeel AL, Taylor EW. Proposed definitions for the audit of postoperative infection: a discussion paper. Surgical Infection Study Group. Ann R Coll Surg Engl. 1991 Nov;73(6):385-8. PMID 1759770
- BACKGROUNDvan Oostendorp S, Elfrink A, Borstlap W, Schoonmade L, Sietses C, Meijerink J, Tuynman J. Intracorporeal versus extracorporeal anastomosis in right hemicolectomy: a systematic review and meta-analysis. Surg Endosc. 2017 Jan;31(1):64-77. doi: 10.1007/s00464-016-4982-y. Epub 2016 Jun 10. PMID 27287905
- BACKGROUNDClavien PA, Barkun J, de Oliveira ML, Vauthey JN, Dindo D, Schulick RD, de Santibanes E, Pekolj J, Slankamenac K, Bassi C, Graf R, Vonlanthen R, Padbury R, Cameron JL, Makuuchi M. The Clavien-Dindo classification of surgical complications: five-year experience. Ann Surg. 2009 Aug;250(2):187-96. doi: 10.1097/SLA.0b013e3181b13ca2. PMID 19638912
- DERIVEDHoyuela C, Guillaumes S, Ardid J, Hidalgo NJ, Bachero I, Trias M, Martrat A. The impact of intracorporeal anastomosis in right laparoscopic colectomy in the surgical site infections and the hospital stay: a cohort study. Updates Surg. 2021 Dec;73(6):2125-2135. doi: 10.1007/s13304-021-00998-5. Epub 2021 Feb 15. PMID 33590349