Clinical trial · Observational
Breath Analysis Based Disease Biomarkers
Development of a Breath Analysis Test for Disease Diagnosis and Prognosis
NCT04341012CI-TRIAL-00101643completedResults postedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of the study is to develop a clinical test based on breath analysis that can be used for disease diagnosis or prognosis.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| COVID19 | — | UNRESOLVED | — |
| Liver Cancer | Malignant Liver Neoplasm | CURATED_EXACT | 0.92 |
| Liver Diseases | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Collection of breath sample | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- label
- Normal
- description
- No known medical conditions
- interventionNames
- Diagnostic Test: Collection of breath sample
- label
- Liver Cirrhosis
- description
- Clinically diagnosed with cirrhosis
- interventionNames
- Diagnostic Test: Collection of breath sample
- label
- COVID-19 tested
- description
- Persons with known test results for COVID-19 RNA
- interventionNames
- Diagnostic Test: Collection of breath sample
- label
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Able to provide informed consent Exclusion Criteria: * None
References
Publications (1)
- RESULTThomas JN, Roopkumar J, Patel T. Machine learning analysis of volatolomic profiles in breath can identify non-invasive biomarkers of liver disease: A pilot study. PLoS One. 2021 Nov 30;16(11):e0260098. doi: 10.1371/journal.pone.0260098. eCollection 2021. PMID 34847181