Clinical trial · Observational
A Retrospective Cohort Study Outcome of Treatment in Asymptomatic Stage 4 Colorectal Cancer
A Retrospective Cohort Study Outcome of Treatment in Asymptomatic Stage 4 Colorectal Cancer : Primary Tumor Resection vs. No Primary Tumor Resection
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
In asymptomatic Stage 4 colorectal cancer, the treatment varies between many hospitals and countries. Some studies found that primary tumor resection had better survival rates and a lower risk of mortality. But many studies found significant benefits in survival in sub groups of the population such as age less than 70 years, WHO performance status \<2, no extra-hepatic metastasis, liver tumor burden \<50%. However some studies showed no survival benefits in primary tumor resection. So this study will focus on survival, adverse events, complications in primary tumor resection and no primary tumor resection in asymptomatic Stage 4 colorectal cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Stage IV Colon Cancer | Malignant Colon Neoplasm | CURATED_BROADER | 0.78 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| primary tumor resection group | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Complication rate
- timeFrame
- 5 year
- description
- The definition of complication defined as symptom that occurred during treatment period such as obstruction , perforation , bleeding , trenesmus.
Secondary outcomes (1)
- measure
- The survival time
- timeFrame
- 5 year
- description
- The survival time defined as time from diagnosis to death or last follow up period
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Asymptomatic stage IV colorectal cancer * pathological prove adenocarcinoma * age \>18 years * no primary tumor related symptom * ECOG performance status \<2 Exclusion Criteria: * symptomatic primary tumor such as obstruction , perforation that required surgery * carcinomatosis peritoneii * patients with secondary cancer diagnosis in 5 years
References
Publications (0)
Data not yet available