Clinical trial · Interventional
To Assess the Efficacy of the LYMPHA in the Prevention of Lymphedema Following Axillary Dissection for Breast Cancer
A Randomized Controlled Trial to Assess the Efficacy of the Lymphatic Microsurgical Preventive Healing Approach (LYMPHA) to Prevent Lymphedema After Axillary Dissection for Breast Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Lymphedema is the Build-up of Lymph Fluid in the Body's Tissue Causing Chronic, Debilitating Swelling. This Commonly Occurs as a Result of a Disruption of the Lymphatic System During Lymph Node Dissection Surgeries. LYMPHA (LYmphatic Microsurgical Preventive Healing Approach) is an Innovative Microsurgical Technique Where Blocked Lymphatic Vessels Are Drained Into the Blood Circulation by Surgically Creating a Shunt Between a Lymphatic Channel and a Blood Vessel Called a Lymphatic-venous Bypass. Recently, LYMPHA Technique Has Been Shown to Prevent Lymphedema When Performed at the Time of Nodal Dissection. We Propose a Prospective Study Evaluating the Effectiveness of LYMPHA Technique Using Objective Clinical Protocol.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lymphedema, Breast Cancer | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| LYMPHA(LYmphatic Microsurgical Preventive Healing Approach) technique | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- LYMPHA technique group
- description
- LVA at the time of Axillary Dissection
- interventionNames
- Procedure: LYMPHA(LYmphatic Microsurgical Preventive Healing Approach) technique
- type
- NO_INTERVENTION
- label
- Non-LYMPHA technique group
- description
- No preventive surgical approach
Primary outcomes (4)
- measure
- lymphatic flow
- timeFrame
- 6 months
- description
- Difference in lymphatic flow between LYMPHA technique group and Non-LYMPHA technique group
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * Node-positive cancer requiring an axillary or lymphadenectomy * Below 30 Body Mass Index Exclusion Criteria: * Patients receiving a sentinel lymph node biopsy * Patients with established preoperative lymphedema * Patients with post-thrombotic syndrome, peripheral vascular disease * Pregnant patients
References
Publications (0)
Data not yet available