Clinical trial · Observational
Personalized Exercise Oncology
Personalized Exercise Oncology (PEXO) - Study
NCT04328038CI-TRIAL-00085398PEXOactive not recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The Goal of the study is to identify trait-homogenous groups of cancer patients in regards to their physical activity associated health literacy. Based on these Groups, individualized exercise protocols and educative strategies can be developed which may increase the efficacy of the exercise therapy and increases the likelihood that patient get involved in physical activity.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Health Behavior | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Survey | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- USA
- description
- Cohort from the USA
- interventionNames
- Other: Survey
- label
- Germany
- description
- Cohort from Germany
- interventionNames
- Other: Survey
Primary outcomes (1)
- measure
- Patient Clusters
- timeFrame
- through study completion, an average of 1 year
- description
- Identification of different, trait-homogenous patient clusters
Secondary outcomes (7)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Histologically confirmed cancer diagnosis * Females and males ≥18 years of age * Undergoing either chemo-, immune-, radio- or anti-hormonal treatment * Last surgery more than 6 weeks in the past * Ability to understand English or German * Be able to provide and understand informed consent * Have an Eastern Cooperative Oncology Group (ECOG) Performance Score of ≤ 2 Exclusion Criteria: * Heart insufficiency \> NYHA III (New York Heart Association) or uncertain arrhythmia * Uncontrolled hypertension * Severe renal dysfunction (GFR \< 30%, Creatinine\> 3mg/dl) * Reduced standing or walking * Current pregnancy * Any other evidence in the medical record of an absolute contraindication for exercise
References
Publications (2)
- DERIVEDGreinacher A, Kuehl R, Mai EK, Goldschmidt H, Wiskemann J, Fleischer A, Rasche L, Dapunt U, Maatouk I. The impact of divergent forms of social support on health-related quality of life in patients with multiple myeloma and its precursor states. J Cancer Res Clin Oncol. 2024 Jan 31;150(2):55. doi: 10.1007/s00432-023-05570-9. PMID 38291214
- DERIVEDKuehl R, Koeppel M, Goldschmidt H, Maatouk I, Rosenberger F, Wiskemann J. Physical activity-related health competence and symptom burden for exercise prescription in patients with multiple myeloma: a latent profile analysis. Ann Hematol. 2023 Nov;102(11):3091-3102. doi: 10.1007/s00277-023-05326-y. Epub 2023 Jun 24. PMID 37355476