Clinical trial · Interventional
LLETZ With Videocolposcopy Versus LLETZ With Binocular Colposcopy
Performance of Large Loop Excision of the Transformation Zone Using Videocolposcopy Versus Binocular Colposcopy in Women With Cervical Dysplasia: a Randomized Controlled Trial.
NCT04326049CI-TRIAL-00059721completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To assess the benefits of performing large Loop excision of the transformation Zone (LLETZ) using videocolposcopy compared to binocular colposcopy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Uterine Cervical Dysplasia | Cervical Intraepithelial Neoplasia | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| LLETZ with binocular colposcope | Device | — | UNRESOLVED |
| LLETZ with videocolposcope | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- LLETZ with videocolposcopy
- description
- The LLETZ procedure will be performed using a videocolposcopy
- interventionNames
- Device: LLETZ with videocolposcope
- type
- ACTIVE_COMPARATOR
- label
- LLETZ with binocular colposcopy
- description
- The LLETZ procedure will be performed using a binocular colposcope
- interventionNames
- Device: LLETZ with binocular colposcope
Primary outcomes (1)
- measure
- the resected cone mass
- timeFrame
- 10 minutes
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * histologically proven cervical dysplasia * colposcopy Prior to conization * informed consent Exclusion Criteria: * significant language barrier * a personal history of conization * pregnancy * the use of blood thinner * unwillingness to participate
References
Publications (1)
- DERIVEDRezniczek GA, Neghabian N, Rehman S, Tempfer CB. Video colposcopy versus headlight for large loop excision of the transformation zone (LLETZ): a randomised trial. Arch Gynecol Obstet. 2022 Feb;305(2):415-423. doi: 10.1007/s00404-021-06331-0. Epub 2021 Nov 21. PMID 34802113