Clinical trial · Interventional
Energy Device Study in Transoral Endoscopic Thyroidectomy
Comparative Analysis Between Harmonic Versus LigaSure in Transoral Endoscopic Thyroidectomy: A Randomized Controlled Trial
NCT04320901CI-TRIAL-00056634unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Open label randomized controlled study, for Harmonic versus Ligasure in transoral endoscopic thyroid surgery.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Thyroid Cancer | Malignant Thyroid Gland Neoplasm | CURATED_EXACT | 0.92 |
| Thyroid Nodule | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Harmonic | Device | — | UNRESOLVED |
| Ligasure | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Harmonic
- description
- Endoscopic procedure will be done by Harmonic ACE7+
- interventionNames
- Device: Harmonic
- type
- EXPERIMENTAL
- label
- Ligasure
- description
- Endoscopic procedure will be done by Ligasure
- interventionNames
- Device: Ligasure
Primary outcomes (3)
- measure
- Operation time
- timeFrame
- During the procedure
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Patients who planned to transoral endoscopic thyroidectomy * Age between 20 to 70 * Voluntarily consenting to the study and study agreement * No local invasion or distant metastasis * Normal vocal cord function in laryngoscopic exam * No significant abnormalities in preoperative laboratory tests Exclusion Criteria: * Take aspirin or antiplatelet drugs within 7 days before admission * Uncontrolled hypertension, diabetes, chronic renal failure, or coagulation disease * History of cardiovascular disease (angina pectoris, heart failure, myocardial infarction, history of coronary artery disease, stroke, transient ischemic attack) * Substance abuse and alcohol abuse * History of esophageal and airway diseases * Patient was participated in other clinical trials within 30 days * History of neck irradiation or surgery * History of severe drug allergies * Pregnant or lactating women
References
Publications (1)
- DERIVEDPark SY, Shin MH, Hwang YM, Choi YS, Yi JW. Comparative analysis between ultrasonic shears versus advanced bipolar device in transoral endoscopic thyroidectomy: a randomized controlled trial. Gland Surg. 2023 Sep 25;12(9):1191-1202. doi: 10.21037/gs-23-227. Epub 2023 Sep 18. PMID 37842523