Clinical trial · Observational
A Explorative Study to Evaluate the Clinical Feasibility of AVATAMED
A Clinical Study to Explore the Feasibility of AVATAMED in Predicting the Cilnical Response to Temozolomide in Glioblastoma Patients, a Single-center, Prospective Study
NCT04313842CI-TRIAL-00044091unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is an exploratory study to evaluate the clinical feasibility of medical deivce 'AVATAMED' for predicting the clinical response to TMZ (temozolomide) in glioblasotma patients.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Glioblastoma | Glioblastoma | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| AVATAMED | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- 6 month PFS rate
- timeFrame
- 6 month
- description
- the fraction of patients without disease progression at 6 months after the TMZ treatment
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 19 Years
- Maximum age
- 90 Years
Show eligibility criteria text
Inclusion Criteria: 1. written informed consent 2. histologically confirmed glioblastoma patients who will take TMZ treatment 3. KPS \>70 4. adequte end-organ function 5. prior major surgery \> 4 weeks (prior minor surgery \> 1weeks) 6. prior standard concurrent chemo-radiation therapy \> 4 weeks 7. prior radiation therapy (including stereotactic radiosurgery) \> 12 weeks Exclusion Criteria: 1. contraindication to TMZ 2. prior anti-cancer therapy except standard of care (\*standard of care includes surgery, Stupp regimen, and radiotherapy) 3. uncontrolled systemic medical illness 4. pregnancy
References
Publications (0)
Data not yet available
No reference posted for this study.