Clinical trial · Observational
Retrospective Study on Referral Patterns for High Risk Patients Post Nephrectomy
Provider Referral Patterns Following Nephrectomy in High-Risk Locoregional Renal Cell Carcinoma
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study aims at estimating the proportion of patients diagnosed with locoregional renal cell carcinoma who are at high risk for recurrence following nephrectomy, describe referral patterns, and characterize treatment in this population. Outcomes including estimation of the incidence of recurrence and disease-free interval following nephrectomy will be reported overall and among the subgroup off patients receiving adjuvant systemic therapy with sunitinib following nephrectomy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Renal Cell Carcinoma | Renal Cell Carcinoma | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| nephrectomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- patients with Renal Cell Carcinoma(RCC)
- description
- Patients diagnosed with RCC who received a nephrectomy between 01Apr2014 and 31Mar2019
- interventionNames
- Procedure: nephrectomy
Primary outcomes (19)
- measure
- Follow-up Duration
- timeFrame
- From index date to the last entry in the medical record, death, or disease recurrence, approximately during 5 years (data observed during 9 months of retrospective study)
- description
- Follow- up time (in years) was duration between index date to the last entry in the medical record, death, or disease recurrence. The date of nephrectomy was considered as index date.
- measure
- Number of Participants Classified According to Follow-up Plan Determined at First Post-operative Visit
- timeFrame
- At first post-nephrectomy visit during approximately during 5 years (data observed during 9 months of retrospective study)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients must meet all of the following inclusion criteria to be eligible for data abstraction: * Diagnosed with locoregional RCC (no distant metastasis at the time of diagnosis) * Underwent a nephrectomy at Duke between 01 April 2014, and 31 December 2019 (final dates determined based on results from part 2 data collection) * Aged 18 years or older at nephrectomy Exclusion Criteria: * none
References
Publications (1)
- DERIVEDDzimitrowicz H, Esterberg E, Miles L, Zanotti G, Borham A, Harrison MR. Referral and adjuvant treatment patterns after nephrectomy in high-risk locoregional renal cell carcinoma. Cancer Med. 2021 Dec;10(24):8891-8898. doi: 10.1002/cam4.4407. Epub 2021 Nov 9. PMID 34751002