Clinical trial · Observational
Diet, Physical Activity and Body Composition Changes During R-CHOP
Prospective Observational Study of Diet, Physical Activity and Body Composition Changes During R-CHOP Treatment for NHL
NCT04293900CI-TRIAL-00047516R-CHOP-OSwithdrawnClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Study never started due to COVID pandemic and lack of study funding.
Summary
Brief summary (as posted)
In this pilot study, observational data will be collected to describe the usual trajectory of changes in dietary intake, ability to be physically active, body composition, environmental exposures, and the gut microbiome over the course of R-CHOP treatment for non-Hodgkin lymphoma (NHL).
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Diffuse Large B Cell Lymphoma | Diffuse Large B-Cell Lymphoma | CURATED_BROADER | 0.80 |
| DLBCL | Diffuse Large B-Cell Lymphoma | ALIAS | 0.90 |
| Non-Hodgkin Lymphoma | Non-Hodgkin Lymphoma | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (8)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 24-hour dietary recall | Other | — | UNRESOLVED |
| fecal sample (optional) | Other | — | UNRESOLVED |
| Functional Assessment of Cancer Treatment - Lymphoma | Other | — | UNRESOLVED |
| Hand grip strength | Other | — | UNRESOLVED |
| International Physical Activity Questionnaire | Other | — | UNRESOLVED |
| Patient-reported outcomes survey | Other | — | UNRESOLVED |
| Pittsburgh Sleep Quality Index | Other | — | UNRESOLVED |
| urine sample (optional) | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Study cohort
- description
- 24-hour dietary recall, hand grip strength, accelerometer, International Physical Activity Questionnaire (IPAQ), Patient-reported outcomes survey (NCI-PRO-CTCAE), Pittsburgh Sleep Quality Index (PSQI), Functional Assessment of Cancer Treatment - Lymphoma (FACT-lym), urine sample (optional), fecal sample (optional)
- interventionNames
- Other: 24-hour dietary recall
- Other: Hand grip strength
- Other: International Physical Activity Questionnaire
- Other: Patient-reported outcomes survey
- Other: Pittsburgh Sleep Quality Index
- Other: Functional Assessment of Cancer Treatment - Lymphoma
- Other: urine sample (optional)
- Other: fecal sample (optional)
Primary outcomes (1)
- measure
- Change in lean body mass (LBM) from baseline to end of R-CHOP chemotherapy
- timeFrame
- baseline and post-R-CHOP chemotherapy (18 weeks)
- description
- change in kilograms of lean body mass as measured from staging CT-scans from pre- to post-R-CHOP chemotherapy.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Diagnosis of one of the non-Hodgkin lymphomas * Scheduled to receive R-CHOP at the George Washington University Cancer Center Exclusion Criteria: * Diagnosis of cancer other than one of the non-Hodgkin lymphomas * Patients who are scheduled to receive their R-CHOP somewhere other than the George Washington University Cancer Center * Patients who are not competent to provide informed consent to participate
References
Publications (0)
Data not yet available
No reference posted for this study.