Clinical trial · Observational
Epigenetics of TNBC in Overweight and Obese Hispanic & Non-Hispanic White Women
Epigenetics of Triple-Negative Breast Cancer in Overweight and Obese Hispanic and Non-Hispanic White Women
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Principal investigator is moving to a new institution. Study is closing.
Summary
Brief summary (as posted)
A key tenet of this project is that of reaching translational human diagnosis and biomarker end points. To lay a foundation and make progress towards these translational goals, investigators will address the following specific aim: To determine if BMI/ obesity differentially influence expression and epigenetic signatures in triple negative breast cancer (TNBC) from Hispanic compared to NHW women.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Triple Negative Breast Cancer | Triple-Negative Breast Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Needle core biopsy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Control group
- description
- Hispanic and NHW women undergoing either a benign breast surgery or prophylactic mastectomy.
- interventionNames
- Procedure: Needle core biopsy
- label
- Newly diagnosed TNBC
- description
- Hispanic and NHW with newly diagnosed TNBC. Patients with TNBC will be eligible regardless of whether their treatment plan is surgery first or chemotherapy first (neoadjuvant chemotherapy).
- interventionNames
- Procedure: Needle core biopsy
Primary outcomes (1)
- measure
- To determine if BMI/ obesity differentially influence expression and epigenetic signatures in TNBC from Hispanic compared to NHW women.
- timeFrame
- Two years
- description
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Hispanic or NHW women * ≥ 18 years of age * scheduled for a breast procedure as standard of care treatment - benign breast surgery or prophylactic mastectomy\\ * Newly diagnosed TNBC - Patients with TNBC will be eligible regardless of whether their treatment plan is surgery first or chemotherapy first (neoadjuvant chemotherapy) * Eligible non-white women could be included Exclusion Criteria: * BRCA1/2 mutation carriers * Family history of breast cancer in a first-degree relative and have NOT had genetic testing for BRCA1/2 * Patients who have already undergone radiation or chemotherapy * Pregnant women * Male * Prisoners
References
Publications (0)
Data not yet available